3-Chloro-4-ethoxyphenylboronic acid
3-Chloro-4-ethoxyphenylboronic acid (CAS: 279261-81-3) is an organoboron compound with the molecular formula ClC6H3(OCH2CH3)B(OH)2 and a molecular weight of 200.43 g/mol. This disubstituted aryl boronic acid serves as a valuable building block in organic synthesis. Its structure makes it useful in cross-coupling reactions, contributing to the development of complex molecules for various research and development applications, particularly within the pharmaceutical and chemical industries.

Organic Synthesis Intermediate
Utilised as a key intermediate in complex organic synthesis, particularly in the construction of carbon-carbon bonds via Suzuki-Miyaura coupling reactions. It enables the introduction of the 3-chloro-4-ethoxyphenyl moiety into target molecules.
Pharmaceutical Research
Serves as a building block in the synthesis of potential pharmaceutical agents. Its specific substitution pattern can be crucial for modulating the biological activity of drug candidates.
Materials Science
Can be employed in the development of novel organic materials where specific electronic or structural properties are required, leveraging the reactivity of the boronic acid group.
| Molecular weight | 200.43 |
|---|---|
| Linear formula | ClC6H3(OCH2CH3)B(OH)2 |
| Melting point | 234-239 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-ethoxyphenylboronic acid used for?
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3-Chloro-4-ethoxyphenylboronic acid is primarily used as an intermediate in organic synthesis, particularly for cross-coupling reactions like the Suzuki-Miyaura coupling, and in pharmaceutical research and materials science.
What is the CAS number and molecular formula for 3-Chloro-4-ethoxyphenylboronic acid?
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The CAS number is 279261-81-3 and the molecular formula is ClC6H3(OCH2CH3)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and grade are available on the product's specification sheet, and it is not represented as USP, BP, or EP grade.
How should 3-Chloro-4-ethoxyphenylboronic acid be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if airborne exposure is possible. Store in a cool, dry place.
Is this chemical a controlled substance?
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Based on the provided data, 3-Chloro-4-ethoxyphenylboronic acid is not listed as a controlled substance. However, users should always comply with local regulations.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs and ships fine chemicals globally, adhering to all necessary export and transportation regulations to ensure safe delivery.
How can I request a sample or quote for 3-Chloro-4-ethoxyphenylboronic acid?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales team directly with your specific requirements.
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