3,5-Difluorobenzylzinc bromide solution
3,5-Difluorobenzylzinc bromide solution (CAS: 308796-30-7) is an organozinc halide supplied by Tech Serve Solutions. With a molecular weight of 272.41 g/mol, this compound is typically provided as a 0.5 M solution in THF. It serves as a valuable reagent in organic synthesis, particularly for cross-coupling reactions and the introduction of the 3,5-difluorobenzyl moiety into various molecular structures. Its controlled handling is essential due to its flammability and reactivity.
- Synonyms
- F2C6H3CH2ZnBr

Organometallic Synthesis
Utilised as a nucleophilic source of the 3,5-difluorobenzyl group in cross-coupling reactions such as Negishi coupling, enabling the formation of carbon-carbon bonds.
Fluorinated Building Block
Introduces the 3,5-difluorobenzyl fragment into complex organic molecules, which is a common structural motif in pharmaceuticals and agrochemicals.
Reagent for Functional Group Transformation
Can be employed in various transformations requiring organozinc reagents for selective functionalisation.
| Molecular weight | 272.41 |
|---|---|
| Linear formula | F2C6H3CH2ZnBr |
| Density | 0.982 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |



Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluorobenzylzinc bromide solution used for?
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3,5-Difluorobenzylzinc bromide solution is primarily used in organic synthesis for introducing the 3,5-difluorobenzyl group via cross-coupling reactions and other transformations requiring organozinc reagents.
What is the CAS number and formula for 3,5-Difluorobenzylzinc bromide solution?
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The CAS number is 308796-30-7 and the linear formula is F2C6H3CH2ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluorobenzylzinc bromide solution at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, or EP grade.
How should 3,5-Difluorobenzylzinc bromide solution be handled safely?
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This compound is highly flammable (Flash Point: -17 °C), causes serious eye irritation, and may cause respiratory irritation. It is also suspected of causing cancer and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.
How is 3,5-Difluorobenzylzinc bromide solution packed and shipped?
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This product is shipped under UN 2924, Hazard Class 8(3), Packing Group II, requiring specialised packaging and handling procedures for hazardous materials.
How can I request a sample or quote?
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To request a sample or quote for 3,5-Difluorobenzylzinc bromide solution, please contact our sales team via the website or by phone.
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