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3,5-Difluorobenzylzinc bromide solution

CAS 308796-30-7F2C6H3CH2ZnBrChemical Synthesis

3,5-Difluorobenzylzinc bromide solution (CAS: 308796-30-7) is an organozinc halide supplied by Tech Serve Solutions. With a molecular weight of 272.41 g/mol, this compound is typically provided as a 0.5 M solution in THF. It serves as a valuable reagent in organic synthesis, particularly for cross-coupling reactions and the introduction of the 3,5-difluorobenzyl moiety into various molecular structures. Its controlled handling is essential due to its flammability and reactivity.

Synonyms
F2C6H3CH2ZnBr
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3,5-Difluorobenzylzinc bromide solution (F2C6H3CH2ZnBr) — chemical structure, CAS 308796-30-7; Chemistry, fine chemical supplied by Tech Serve Solutions
AlkylChemical SynthesisOrganometallic ReagentsOrganozinc Halides
01 /Applications

Organometallic Synthesis

Utilised as a nucleophilic source of the 3,5-difluorobenzyl group in cross-coupling reactions such as Negishi coupling, enabling the formation of carbon-carbon bonds.

Fluorinated Building Block

Introduces the 3,5-difluorobenzyl fragment into complex organic molecules, which is a common structural motif in pharmaceuticals and agrochemicals.

Reagent for Functional Group Transformation

Can be employed in various transformations requiring organozinc reagents for selective functionalisation.

02 /Properties
Molecular weight272.41
Linear formulaF2C6H3CH2ZnBr
Density0.982 g/mL at 25 °C
Concentration0.5 M in THF
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H351Suspected of causing cancer

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P281Use personal protective equipment as required
  • P305IF IN EYES
Flash point-17 °C / 1.4 °F
Transport (UN / ADR)UN 2924 8(3) / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xn
Risk statements (R)11-14-19-36/37-40
Safety statements (S)16-26-36/37
Supplemental hazardsMay form explosive peroxides.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
308796-30-7
MDL number
MFCD01311400
PubChem substance
24873284
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,5-Difluorobenzylzinc bromide solution used for?

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3,5-Difluorobenzylzinc bromide solution is primarily used in organic synthesis for introducing the 3,5-difluorobenzyl group via cross-coupling reactions and other transformations requiring organozinc reagents.

What is the CAS number and formula for 3,5-Difluorobenzylzinc bromide solution?

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The CAS number is 308796-30-7 and the linear formula is F2C6H3CH2ZnBr.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3,5-Difluorobenzylzinc bromide solution at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, or EP grade.

How should 3,5-Difluorobenzylzinc bromide solution be handled safely?

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This compound is highly flammable (Flash Point: -17 °C), causes serious eye irritation, and may cause respiratory irritation. It is also suspected of causing cancer and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.

How is 3,5-Difluorobenzylzinc bromide solution packed and shipped?

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This product is shipped under UN 2924, Hazard Class 8(3), Packing Group II, requiring specialised packaging and handling procedures for hazardous materials.

How can I request a sample or quote?

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To request a sample or quote for 3,5-Difluorobenzylzinc bromide solution, please contact our sales team via the website or by phone.

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