3,5-Difluorobenzylamine
3,5-Difluorobenzylamine (CAS: 90390-27-5) is an organic compound with the linear formula F₂C₆H₃CH₂NH₂ and a molecular weight of 143.13 g/mol. This fluorinated building block serves as a key intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its unique difluorophenyl moiety allows for the introduction of specific structural features into more complex molecules, facilitating the development of novel compounds with tailored properties.
- Synonyms
- F2C6H3CH2NH2

Pharmaceutical Intermediates
Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The difluorobenzyl group can modulate lipophilicity and metabolic stability of drug molecules.
Agrochemical Development
Serves as a building block for creating new pesticides, herbicides, and fungicides. Fluorinated compounds often exhibit enhanced biological activity and modified environmental persistence.
Material Science
Can be incorporated into polymers or functional materials where specific electronic or physical properties are desired, leveraging the influence of fluorine substituents.
Research and Development
A versatile reagent for academic and industrial research laboratories exploring novel synthetic routes and chemical entities.
| Molecular weight | 143.13 |
|---|---|
| Linear formula | F2C6H3CH2NH2 |
| Assay | 96% |
| Boiling point | 184 °C(lit.) |
| Density | 1.21 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.491(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluorobenzylamine used for?
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3,5-Difluorobenzylamine is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, as well as in materials science research.
What is the CAS number and molecular formula for 3,5-Difluorobenzylamine?
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The CAS number is 90390-27-5, and the molecular formula is F₂C₆H₃CH₂NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluorobenzylamine with a minimum assay of 96%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3,5-Difluorobenzylamine be handled safely?
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3,5-Difluorobenzylamine is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, gloves, and respirators, must be used. Handle in a well-ventilated area and follow all safety precautions.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,5-Difluorobenzylamine. Please contact us for export inquiries.
How can I request a quote or sample?
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To request a quote or a sample of 3,5-Difluorobenzylamine, please contact our sales team through the website or by phone. Specify your requirements, including quantity and delivery location.
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