2-Fluoro-6-(trifluoromethyl)phenyl isocyanate
2-Fluoro-6-(trifluoromethyl)phenyl isocyanate (CAS: 190774-53-9, Formula: C8H3F4NO) is a specialized organic compound with a molecular weight of 205.11. This fluorinated aromatic isocyanate serves as a versatile building block in chemical synthesis. Its reactivity makes it valuable for introducing the 2-fluoro-6-(trifluoromethyl)phenyl group into various molecular structures, finding utility in research and development across diverse chemical sectors.
Synthesis of Novel Organic Compounds
This isocyanate is employed as a key intermediate in the synthesis of complex organic molecules. It can react with nucleophiles like alcohols, amines, and thiols to form carbamates, ureas, and thiocarbamates, respectively.
Pharmaceutical Intermediate
The compound's unique fluorinated structure makes it a valuable precursor for the development of new pharmaceutical agents. It can be incorporated into drug candidates to modulate properties such as lipophilicity and metabolic stability.
Agrochemical Research
It is utilized in the research and development of new agrochemicals. The trifluoromethyl and fluorine substituents can enhance the biological activity and persistence of pesticides and herbicides.
Materials Science
This isocyanate can be used in the functionalization of polymers or the synthesis of novel materials, where its specific electronic and steric properties can impart desired characteristics.
| Molecular weight | 205.11 |
|---|---|
| Linear formula | FC6H3(CF3)NCO |
| Assay | 97% |
| Boiling point | 47 °C/2.5 mmHg(lit.) |
| Density | 1.436 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.461(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | UN 2922 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-6-(trifluoromethyl)phenyl isocyanate used for?
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2-Fluoro-6-(trifluoromethyl)phenyl isocyanate is primarily used as a versatile building block in organic synthesis for creating complex molecules, including pharmaceutical intermediates and agrochemicals.
What is the CAS number and chemical formula?
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The CAS number is 190774-53-9, and the chemical formula is C8H3F4NO (FC6H3(CF3)NCO).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-6-(trifluoromethyl)phenyl isocyanate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Fluoro-6-(trifluoromethyl)phenyl isocyanate be handled?
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This compound is harmful if swallowed, in contact with skin, or inhaled, and causes skin and eye irritation, and may cause respiratory irritation. Always use appropriate personal protective equipment, including eyeshields, face shields, gloves, and a suitable respirator, and work in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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This chemical is packed according to international shipping regulations and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 2-Fluoro-6-(trifluoromethyl)phenyl isocyanate?
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Please contact Tech Serve Solutions directly through our website or by phone to request a sample or a quotation for 2-Fluoro-6-(trifluoromethyl)phenyl isocyanate.
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