2-Fluoro-6-(trifluoromethyl)phenylacetonitrile
2-Fluoro-6-(trifluoromethyl)phenylacetonitrile (CAS: 179946-34-0) is a fluorinated aromatic nitrile with the molecular formula FC<sub>6</sub>H<sub>3</sub>(CF<sub>3</sub>)CH<sub>2</sub>CN and a molecular weight of 203.14. This compound serves as a valuable building block in organic synthesis. Its structure, featuring both fluorine and trifluoromethyl substituents, makes it useful in the development of novel pharmaceuticals and agrochemicals where modified electronic and lipophilic properties are desired.
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where fluorinated phenylacetonitrile moieties are incorporated to influence drug efficacy and metabolic stability.
Agrochemical Development
Serves as a precursor for novel pesticides and herbicides, leveraging its fluorinated structure to enhance biological activity and environmental persistence profiles.
Organic Synthesis Building Block
A versatile reagent for introducing the 2-fluoro-6-(trifluoromethyl)phenylacetonitrile fragment into complex organic molecules. Useful in research and development for creating new chemical entities.
Materials Science Research
Potentially employed in the development of advanced materials where fluorinated organic compounds are required for specific electronic or physical properties.
| Molecular weight | 203.14 |
|---|---|
| Linear formula | FC6H3(CF3)CH2CN |
| Assay | 97% |
| Boiling point | 229 °C(lit.) |
| Density | 1.363 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.449(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-6-(trifluoromethyl)phenylacetonitrile used for?
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2-Fluoro-6-(trifluoromethyl)phenylacetonitrile (CAS: 179946-34-0) is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 2-Fluoro-6-(trifluoromethyl)phenylacetonitrile?
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The CAS number is 179946-34-0 and the molecular formula is FC<sub>6</sub>H<sub>3</sub>(CF<sub>3</sub>)CH<sub>2</sub>CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-6-(trifluoromethyl)phenylacetonitrile with an assay of 97%. This is a technical/research grade and TSS does not represent it as USP, BP, or EP grade.
How should 2-Fluoro-6-(trifluoromethyl)phenylacetonitrile be handled?
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Based on GHS information, this compound is harmful if swallowed, in contact with skin, or if inhaled. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., type ABEK respirator filter), should be used. Handle in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports fine chemicals globally, adhering to all relevant transport regulations. Please contact us for specific details regarding packaging and shipping for your region.
How can I request a quote or sample?
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To request a quote or a sample of 2-Fluoro-6-(trifluoromethyl)phenylacetonitrile, please visit the product page on our website and use the 'Request a Quote' or 'Request a Sample' function, or contact our sales team directly.
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