3,5-Difluorobenzyl bromide
3,5-Difluorobenzyl bromide (CAS: 141776-91-2; MFCD00010304) is a halogenated organic compound with the molecular formula F₂C₆H₃CH₂Br and a molecular weight of 207.02 g/mol. It serves as a valuable fluorinated building block in organic synthesis, primarily employed in the preparation of more complex molecules within the pharmaceutical and agrochemical industries. Its specific structure makes it a useful intermediate for introducing the 3,5-difluorobenzyl moiety.
- IUPAC
- α-Bromo-3,5-difluorotoluene
- Synonyms
- F2C6H3CH2Brα-Bromo-3,5-difluorotoluene
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), leveraging the unique electronic and steric properties conferred by the difluorinated phenyl ring for drug discovery and development.
Agrochemical Synthesis
Serves as a key building block for novel pesticides, herbicides, and fungicides, where fluorinated aromatic structures can enhance efficacy and metabolic stability.
Organic Synthesis Reagent
A versatile reagent for introducing the 3,5-difluorobenzyl group into organic molecules through various coupling and alkylation reactions.
Materials Science Research
Explored as a component in the development of new functional materials, where fluorine substitution can influence properties like thermal stability and dielectric constants.
| Molecular weight | 207.02 |
|---|---|
| Linear formula | F2C6H3CH2Br |
| Assay | 98% |
| Boiling point | 65 °C/4.5 mmHg(lit.) |
| Density | 1.6 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.521(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluorobenzyl bromide used for?
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3,5-Difluorobenzyl bromide is primarily used as a building block in organic synthesis, particularly for introducing the 3,5-difluorobenzyl moiety into pharmaceutical intermediates, agrochemicals, and novel materials.
What is the CAS number and formula for 3,5-Difluorobenzyl bromide?
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The CAS number is 141776-91-2 and the linear formula is F₂C₆H₃CH₂Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluorobenzyl bromide with an assay of 98%. This product is intended for research and chemical synthesis and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 3,5-Difluorobenzyl bromide be handled safely?
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3,5-Difluorobenzyl bromide is a corrosive substance (H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including full-face respirators, gloves, and goggles, must be worn. Handle in a well-ventilated area and follow all safety precautions outlined in the Safety Data Sheet.
Is 3,5-Difluorobenzyl bromide a controlled substance?
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The provided data does not indicate that 3,5-Difluorobenzyl bromide is a controlled substance.
How is 3,5-Difluorobenzyl bromide packed, shipped, and exported?
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Tech Serve Solutions exports fine chemicals globally, adhering to all relevant transportation regulations. Specific packing and shipping details are available upon request and depend on the destination and quantity ordered.
How can I request a quote or sample?
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To request a quote or a sample of 3,5-Difluorobenzyl bromide, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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