3,5-Difluorobenzenesulfonyl chloride
3,5-Difluorobenzenesulfonyl chloride (CAS: 210532-25-5) is a key organic fluorinated building block with the molecular formula C6H3ClF2O2S. Its structure, featuring a sulfonyl chloride group and two fluorine atoms on the benzene ring, makes it a valuable intermediate in organic synthesis. This compound is primarily used in the chemical industry for the development of novel compounds and materials, leveraging its reactive sulfonyl chloride moiety for various chemical transformations.
- Synonyms
- F2C6H3SO2Cl

Organic Synthesis Intermediate
Utilised as a building block in the synthesis of complex organic molecules. The sulfonyl chloride functionality readily reacts with nucleophiles, enabling the introduction of the 3,5-difluorobenzenesulfonyl group into target structures.
Pharmaceutical Research
Serves as an intermediate in the development of potential pharmaceutical agents. Fluorinated compounds are often explored for their enhanced metabolic stability and binding properties in drug discovery.
Material Science
Can be employed in the creation of specialised polymers and materials where the incorporation of fluorinated aromatic rings imparts specific properties such as thermal stability or altered electronic characteristics.
| Molecular weight | 212.60 |
|---|---|
| Linear formula | F2C6H3SO2Cl |
| Assay | 97% |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluorobenzenesulfonyl chloride used for?
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3,5-Difluorobenzenesulfonyl chloride is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals and materials, owing to its reactive sulfonyl chloride group and fluorinated aromatic structure.
What is the CAS number and formula for 3,5-Difluorobenzenesulfonyl chloride?
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The CAS number is 210532-25-5, and its linear formula is F2C6H3SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluorobenzenesulfonyl chloride with a minimum assay of 97%. It is supplied as a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations for handling 3,5-Difluorobenzenesulfonyl chloride?
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This compound is classified as Danger (GHS05) and can cause severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, is essential. Handle only in well-ventilated areas or under a fume hood.
How is 3,5-Difluorobenzenesulfonyl chloride packed and shipped?
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3,5-Difluorobenzenesulfonyl chloride is packed and shipped in compliance with relevant transport regulations, including UN 3261 classification for corrosive solids. TSS is experienced in exporting chemicals globally.
How can I request a sample or quote for 3,5-Difluorobenzenesulfonyl chloride?
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To request a sample or obtain a quote, please contact our sales department through the website or by calling our main office. Please reference the product name and CAS number.
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