3,5-Difluorobenzoic acid
3,5-Difluorobenzoic acid (CAS 455-40-3), with the molecular formula C7H4F2O2 and a molecular weight of 158.10 g/mol, is a valuable fluorinated aromatic carboxylic acid. It serves as a key building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its difluorinated structure offers unique electronic properties for incorporation into complex molecular architectures. Tech Serve Solutions supplies this compound with an assay of 97% for research and development purposes.
- Synonyms
- 3,5-Difluorobenzoic acidF2C6H3CO2H

Pharmaceutical Intermediate
3,5-Difluorobenzoic acid is utilised as a precursor in the synthesis of various active pharmaceutical ingredients (APIs). Its fluorinated phenyl ring can enhance metabolic stability and lipophilicity in drug candidates.
Agrochemical Synthesis
This compound finds application in the creation of novel pesticides and herbicides. The fluorine atoms can influence the biological activity and environmental persistence of agrochemical products.
Organic Building Block
As a versatile building block, 3,5-Difluorobenzoic acid enables the construction of complex organic molecules. It is employed in academic research and industrial R&D for exploring new chemical entities.
Materials Science
The specific electronic characteristics imparted by the two fluorine atoms make this acid a potential component in the development of advanced materials, such as liquid crystals or polymers.
| Molecular weight | 158.10 |
|---|---|
| Linear formula | F2C6H3CO2H |
| Assay | 97% |
| Melting point | 121-123 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluorobenzoic acid used for?
+
3,5-Difluorobenzoic acid is primarily used as an intermediate and building block in organic synthesis, particularly for pharmaceuticals, agrochemicals, and materials science research.
What is the CAS number and chemical formula for 3,5-Difluorobenzoic acid?
+
The CAS number is 455-40-3 and the linear chemical formula is F2C6H3CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,5-Difluorobenzoic acid with an assay of 97%. This product is intended for research and development and is not supplied as USP, BP, or EP grade.
How should 3,5-Difluorobenzoic acid be handled safely?
+
Handling requires caution due to its irritant properties. Wear appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Refer to the safety data sheet for comprehensive information.
Is 3,5-Difluorobenzoic acid available for export?
+
Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, including 3,5-Difluorobenzoic acid.
How can I request a sample or a quote for 3,5-Difluorobenzoic acid?
+
Please contact our sales team via the website or by telephone to request a sample or a quotation for 3,5-Difluorobenzoic acid.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis