3,5-Difluoronitrobenzene
3,5-Difluoronitrobenzene (CAS 2265-94-3) is an organic compound with the molecular formula F2C6H3NO2 and a molecular weight of 159.09 g/mol. This fluorinated nitroaromatic serves as a valuable building block in organic synthesis. Its unique structure, featuring two fluorine atoms and a nitro group on a benzene ring, makes it a versatile intermediate for the preparation of more complex molecules, particularly in the fields of pharmaceuticals and agrochemicals. Available from TSS with an assay of 99%.
- Synonyms
- F2C6H3NO2

Pharmaceutical Intermediate
3,5-Difluoronitrobenzene is employed in the synthesis of active pharmaceutical ingredients (APIs). The presence of fluorine atoms can enhance metabolic stability and bioavailability of drug candidates.
Agrochemical Synthesis
This compound acts as a precursor in the development of novel agrochemicals. Its fluorinated structure can contribute to the efficacy and persistence of pesticides and herbicides.
Organic Synthesis Building Block
As a difluorinated aromatic, it is useful in introducing fluorinated phenyl moieties into larger molecules. It can undergo various chemical transformations, including reduction of the nitro group to an amine.
Material Science Research
Potential applications exist in the synthesis of specialty materials where fluorinated aromatic units are desired for their electronic or physical properties.
| Molecular weight | 159.09 |
|---|---|
| Linear formula | F2C6H3NO2 |
| Assay | 99% |
| Boiling point | 176-177 °C(lit.) |
| Density | 1.407 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.499(lit.) |
| Melting point | 17 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluoronitrobenzene used for?
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3,5-Difluoronitrobenzene (CAS 2265-94-3) is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 3,5-Difluoronitrobenzene?
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The CAS number is 2265-94-3, and its chemical formula is F2C6H3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluoronitrobenzene with a purity of 99% (assay). We do not represent this product as USP, BP, or EP grade.
How should 3,5-Difluoronitrobenzene be handled safely?
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3,5-Difluoronitrobenzene is classified with Warning signal word and hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment includes eyeshields, gloves, and suitable respiratory protection. Refer to the Safety Data Sheet for detailed handling instructions.
Is 3,5-Difluoronitrobenzene a controlled substance?
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The provided data does not indicate that 3,5-Difluoronitrobenzene is a controlled substance.
How is 3,5-Difluoronitrobenzene shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, adhering to all relevant shipping and export regulations for chemical products.
How can I request a quote or sample for 3,5-Difluoronitrobenzene?
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Please contact our sales team via the website or by phone to request a quote or a sample of 3,5-Difluoronitrobenzene.
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