3,5-Difluorophenol
3,5-Difluorophenol (CAS: 2713-34-0) is an organofluorine compound with the molecular formula F₂C₆H₃OH and a molecular weight of 130.09 g/mol. This fluorinated phenol serves as a valuable building block in organic synthesis. Its difluorinated aromatic ring makes it a key intermediate for the preparation of more complex fluorinated molecules utilised in pharmaceuticals, agrochemicals, and materials science.
- Synonyms
- F2C6H3OH1,3-Difluoro-5-hydroxybenzene

Pharmaceutical Intermediates
3,5-Difluorophenol is employed as a crucial starting material in the synthesis of various pharmaceutical agents. Its fluorine atoms can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Development
This compound finds application in the development of novel agrochemicals, including herbicides and pesticides. The incorporation of fluorine can enhance the efficacy and metabolic stability of these agents.
Materials Science
The unique electronic properties conferred by the fluorine substituents make 3,5-Difluorophenol a useful precursor for advanced materials, such as liquid crystals and polymers.
Organic Synthesis Building Block
As a versatile building block, 3,5-Difluorophenol enables the introduction of a difluorophenyl moiety into target molecules across various chemical research and development sectors.
| Molecular weight | 130.09 |
|---|---|
| Linear formula | F2C6H3OH |
| Assay | 99% |
| Solubility | ethanol: soluble50, clear, colorless to faint yellow or tan (mg/mL) |
| Melting point | 54-57 °C(lit.) |


Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluorophenol used for?
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3,5-Difluorophenol is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates, agrochemicals, and advanced materials.
What is the CAS number and molecular formula for 3,5-Difluorophenol?
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The CAS number for 3,5-Difluorophenol is 2713-34-0, and its molecular formula is F₂C₆H₃OH.
What grade and purity does Tech Serve Solutions supply for 3,5-Difluorophenol?
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Tech Serve Solutions supplies 3,5-Difluorophenol with an assay of 99%. This product is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the main hazards associated with 3,5-Difluorophenol?
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3,5-Difluorophenol is a flammable solid (H228) and is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
How is 3,5-Difluorophenol handled and stored?
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Handle 3,5-Difluorophenol with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Store in a cool, well-ventilated place away from heat, sparks, and open flames. Keep container tightly closed. It is a flammable solid.
Can Tech Serve Solutions export 3,5-Difluorophenol internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can handle international shipments of 3,5-Difluorophenol in compliance with regulations.
How can I request a quote or sample for 3,5-Difluorophenol?
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To request a quote or sample, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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