2-(Trifluoromethoxy)benzoyl chloride
2-(Trifluoromethoxy)benzoyl chloride (CAS: 162046-61-9; Formula: C8H4ClF3O2; Molar Mass: 224.56 g/mol) is a reactive organic acid halide. It serves as a valuable building block in organic synthesis, particularly for introducing the 2-(trifluoromethoxy)benzoyl moiety into molecules. Its high reactivity makes it useful in acylation reactions for the development of novel compounds in pharmaceuticals and materials science.
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its reactive acyl chloride group readily participates in reactions such as Friedel-Crafts acylation and esterification.
Pharmaceutical Research
A building block for the creation of novel pharmaceutical agents. The trifluoromethoxy group can influence lipophilicity and metabolic stability of drug candidates.
Materials Science
Employed in the development of advanced materials where the incorporation of fluorinated organic structures is desired for specific properties.
| Molecular weight | 224.56 |
|---|---|
| Empirical formula | C8H4ClF3O2 |
| Assay | 98% |
| Density | 1.435 g/mL at 25 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 102 °C / 215.6 °F |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethoxy)benzoyl chloride used for?
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2-(Trifluoromethoxy)benzoyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly in pharmaceutical research and materials science.
What is the CAS number and formula for 2-(Trifluoromethoxy)benzoyl chloride?
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The CAS number is 162046-61-9 and the empirical formula is C8H4ClF3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethoxy)benzoyl chloride with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-(Trifluoromethoxy)benzoyl chloride be handled?
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This compound is classified as Danger, causing severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-(Trifluoromethoxy)benzoyl chloride.
How can I request a quote or sample?
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Please contact our sales department via the website or phone to request a quote or sample of 2-(Trifluoromethoxy)benzoyl chloride.
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