2-(Trifluoromethoxy)phenyl isothiocyanate
2-(Trifluoromethoxy)phenyl isothiocyanate (CAS: 175205-33-1; Formula: CF3OC6H4NCS) is a valuable organic building block with a molecular weight of 219.18. This compound, featuring a trifluoromethoxy group and an isothiocyanate functional moiety, serves as a versatile intermediate in chemical synthesis, particularly for the development of novel organic molecules and materials. Its properties make it useful in various research and development applications.
Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of complex organic molecules. Its reactive isothiocyanate group allows for facile derivatisation in the construction of heterocycles and other advanced chemical structures.
Pharmaceutical Research
Serves as a precursor in the development of potential pharmaceutical agents. The trifluoromethoxy phenyl moiety is a common feature in biologically active compounds, influencing lipophilicity and metabolic stability.
Materials Science
The unique structure of this compound can be incorporated into functional materials, contributing to novel properties in polymers or specialised organic materials.
| Molecular weight | 219.18 |
|---|---|
| Linear formula | CF3OC6H4NCS |
| Assay | 96% |
| Boiling point | 215 °C(lit.) |
| Density | 1.354 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.543(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Transport (UN / ADR) | UN 1760 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethoxy)phenyl isothiocyanate used for?
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2-(Trifluoromethoxy)phenyl isothiocyanate is primarily used as a versatile building block in organic synthesis, particularly for the development of pharmaceuticals and advanced organic materials.
What are the CAS number and molecular formula?
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The CAS number for 2-(Trifluoromethoxy)phenyl isothiocyanate is 175205-33-1, and its molecular formula is CF3OC6H4NCS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethoxy)phenyl isothiocyanate with a minimum purity of 96%. This product is suitable for research and general chemical synthesis and is not supplied as USP, BP, or EP grade.
How should 2-(Trifluoromethoxy)phenyl isothiocyanate be handled safely?
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This compound causes severe skin burns and eye damage (H314). Handle with extreme caution, using appropriate personal protective equipment including gloves, goggles, face shields, and respiratory protection. Ensure adequate ventilation and follow emergency procedures in case of exposure.
How is this chemical packed and exported?
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2-(Trifluoromethoxy)phenyl isothiocyanate is carefully packed in UN-approved packaging suitable for hazardous materials (UN 1760, Class 8, PG II). Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant international shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample of 2-(Trifluoromethoxy)phenyl isothiocyanate, please contact our sales department via the website or by phone, providing your specific requirements and shipping details.
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