2-(Trifluoromethoxy)phenyl isocyanate
2-(Trifluoromethoxy)phenyl isocyanate (CAS: 182500-26-1; Formula: CF3OC6H4NCO; MW: 203.12) is a reactive organic compound supplied by Tech Serve Solutions. This isocyanate derivative is primarily utilised as a building block in chemical synthesis, particularly in the development of complex organic molecules. Its trifluoromethoxy group imparts unique electronic properties, making it valuable in pharmaceutical and materials science research.
Organic Synthesis Intermediate
Serves as a versatile intermediate in the synthesis of diverse organic compounds. Its isocyanate functionality readily reacts with nucleophiles, enabling the introduction of the 2-(trifluoromethoxy)phenyl moiety into target molecules.
Pharmaceutical Research
Utilised in the discovery and development of novel pharmaceutical agents. The trifluoromethoxy group can influence lipophilicity and metabolic stability, desirable attributes in drug candidates.
Materials Science
Can be employed in the development of advanced materials. The incorporation of fluorinated groups can modify material properties such as thermal stability and surface characteristics.
| Molecular weight | 203.12 |
|---|---|
| Linear formula | CF3OC6H4NCO |
| Assay | 95% |
| Density | 1.35 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.455(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 3080 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-37/38-41 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethoxy)phenyl isocyanate used for?
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2-(Trifluoromethoxy)phenyl isocyanate is primarily used as a building block in organic synthesis, research, and the development of pharmaceuticals and advanced materials.
What are the CAS number and chemical formula for 2-(Trifluoromethoxy)phenyl isocyanate?
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The CAS number is 182500-26-1 and the chemical formula is CF3OC6H4NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethoxy)phenyl isocyanate with an assay of 95%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety hazards associated with 2-(Trifluoromethoxy)phenyl isocyanate?
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This compound is flammable (H226), toxic if swallowed (H301), causes skin irritation (H315), serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used. Always consult the Safety Data Sheet before handling.
How is 2-(Trifluoromethoxy)phenyl isocyanate typically shipped?
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2-(Trifluoromethoxy)phenyl isocyanate is shipped as a hazardous material according to UN 3080, Class 6.1, Packing Group II.
How can I request a sample or quote for 2-(Trifluoromethoxy)phenyl isocyanate?
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To request a sample or a quote, please contact our sales team through the website or by calling our office directly.
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