3-Bromo-2-ethoxy-5-fluorophenylboronic acid
3-Bromo-2-ethoxy-5-fluorophenylboronic acid (CAS: 352534-82-8) is an organoboron compound with the molecular formula BrC6H2OC2H5B(OH)2 and a molecular weight of 262.87. This substituted phenylboronic acid serves as a valuable building block in organic synthesis. It is primarily utilised in the development of novel organic molecules, particularly within the pharmaceutical and agrochemical sectors, owing to its utility in cross-coupling reactions and the introduction of complex aryl moieties.

Organic Synthesis Intermediate
This compound is a key intermediate in the synthesis of complex organic molecules. Its boronic acid functionality makes it suitable for various cross-coupling reactions, such as Suzuki-Miyaura coupling.
Pharmaceutical Research
Utilised in medicinal chemistry for the development of new drug candidates. The unique substitution pattern allows for the creation of novel pharmacophores with potential therapeutic activity.
Agrochemical Development
Employed in the synthesis of new agrochemicals, including herbicides, insecticides, and fungicides, contributing to crop protection solutions.
Material Science
Can be used in the preparation of advanced materials and organic electronic components, leveraging its specific structural features.
| Molecular weight | 262.87 |
|---|---|
| Linear formula | BrC6H2OC2H5B(OH)2 |
| Melting point | 105-110 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-2-ethoxy-5-fluorophenylboronic acid used for?
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3-Bromo-2-ethoxy-5-fluorophenylboronic acid is used as a building block in organic synthesis, particularly in pharmaceutical and agrochemical research, and for the development of advanced materials. It is valuable for cross-coupling reactions like Suzuki-Miyaura coupling.
What is the CAS number and formula for 3-Bromo-2-ethoxy-5-fluorophenylboronic acid?
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The CAS number is 352534-82-8, and the linear formula is BrC6H2OC2H5B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and grade are detailed in the product specifications. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
What are the safety precautions for handling this chemical?
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This compound is a Warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (NIOSH N95), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is 3-Bromo-2-ethoxy-5-fluorophenylboronic acid packed and exported?
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Tech Serve Solutions provides secure and compliant packaging suitable for global export, adhering to international shipping regulations for chemical substances.
How can I request a sample or quote?
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Please contact the Tech Serve Solutions sales team via our website or direct enquiry channels to request a quotation or a sample for evaluation.
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