4-Acetamidobenzenesulfonyl azide
4-Acetamidobenzenesulfonyl azide (CAS 2158-14-7), with the molecular formula C8H7N3O3S and a molecular weight of 240.24 g/mol, is a valuable organic reagent. It serves as a potent diazo transfer agent and hydroazidation catalyst. This compound is primarily employed in chemical synthesis for the introduction of azide functionalities, facilitating C-X bond formation and enabling various applications in chemical biology and conjugation chemistry.
- IUPAC
- p-ABSA

Diazo Transfer Agent
4-Acetamidobenzenesulfonyl azide is utilised as a reagent for the transfer of a diazo group in organic synthesis. It is a reliable source for introducing the N3 moiety into various organic molecules.
Hydroazidation Catalyst
This compound acts as a catalyst in hydroazidation reactions, which are crucial for the facile preparation of organoazides. This facilitates the synthesis of nitrogen-containing compounds.
Building Block in Organic Synthesis
As an organic building block, 4-Acetamidobenzenesulfonyl azide is used in the construction of more complex molecules. Its reactive azide group allows for further functionalization and diverse synthetic transformations.
Chemical Biology and Conjugation Chemistry
The compound finds application in chemical biology and conjugation chemistry due to the utility of azide groups in click chemistry reactions. This enables the linking of biomolecules and other chemical entities.
| Molecular weight | 240.24 |
|---|---|
| Linear formula | CH3CONHC6H4SO2N3 |
| Assay | 97% |
| Application | Hydroazidation Catalyst for Facile Preparation of OrganoazidesDiazo transfer agent.1,2,3 |
| Melting point | 107-111 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Acetamidobenzenesulfonyl azide used for?
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4-Acetamidobenzenesulfonyl azide is used as a diazo transfer agent and a hydroazidation catalyst in organic synthesis, facilitating the preparation of organoazides and enabling C-X bond formation. It is also employed in chemical biology and conjugation chemistry.
What is the CAS number and molecular formula for 4-Acetamidobenzenesulfonyl azide?
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The CAS number is 2158-14-7 and the molecular formula is C8H7N3O3S.
What grade and purity does Tech Serve Solutions supply for 4-Acetamidobenzenesulfonyl azide?
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Tech Serve Solutions supplies 4-Acetamidobenzenesulfonyl azide with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 4-Acetamidobenzenesulfonyl azide be handled safely?
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Handle 4-Acetamidobenzenesulfonyl azide with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid dust formation. It is classified as an irritant (H315, H319, H335).
Is 4-Acetamidobenzenesulfonyl azide a controlled substance?
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The provided data does not indicate that 4-Acetamidobenzenesulfonyl azide is a controlled substance.
How is 4-Acetamidobenzenesulfonyl azide packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant regulations to ensure safe and compliant delivery.
How can I request a sample or quote for 4-Acetamidobenzenesulfonyl azide?
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To request a sample or quote for 4-Acetamidobenzenesulfonyl azide, please use the contact form on our website or contact our sales department directly.
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