2-(Trifluoromethoxy)aniline
2-(Trifluoromethoxy)aniline (CAS: 1535-75-7), with the molecular formula CF3OC6H4NH2 and a molecular weight of 177.12 g/mol, is a specialised aromatic amine. It is a valuable building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique trifluoromethoxy substituent imparts distinct electronic and lipophilic properties, making it a sought-after intermediate for creating novel molecules with specific functionalities. Tech Serve Solutions offers this compound for research and development purposes.
- IUPAC
- α,α,α-Trifluoro-o-anisidine
- Synonyms
- α,α,α-Trifluoro-o-anisidine

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), leveraging its trifluoromethoxy group for tailored drug design. This building block is key in creating complex molecules for various therapeutic areas.
Agrochemical Synthesis
Serves as a precursor for developing novel pesticides and herbicides. The incorporation of the trifluoromethoxy moiety can enhance the efficacy and stability of agrochemical products.
Organic Building Block
A versatile intermediate in general organic synthesis, enabling the introduction of the trifluoromethoxy-substituted aniline fragment into various organic structures. This facilitates the creation of diverse chemical entities.
Materials Science Research
Explored for potential applications in advanced materials, where its unique chemical properties may contribute to the development of new polymers or functional materials.
| Molecular weight | 177.12 |
|---|---|
| Linear formula | CF3OC6H4NH2 |
| Assay | 95% |
| Boiling point | 61-63 °C/15 mmHg(lit.) |
| Density | 1.301 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.461(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 54 °C / 129.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22-36/37/38 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethoxy)aniline used for?
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2-(Trifluoromethoxy)aniline is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is also employed in materials science research.
What is the CAS number and chemical formula for 2-(Trifluoromethoxy)aniline?
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The CAS number is 1535-75-7, and the chemical formula is CF3OC6H4NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethoxy)aniline with an assay of 95%. This product is intended for laboratory and research use; we do not represent it as USP, BP, or EP grade.
How should 2-(Trifluoromethoxy)aniline be handled safely?
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Handle with care in a well-ventilated area. This compound is flammable and harmful if swallowed, inhaled, or in contact with skin. It can cause skin and serious eye irritation, and respiratory irritation. Always wear appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator.
Is 2-(Trifluoromethoxy)aniline flammable?
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Yes, 2-(Trifluoromethoxy)aniline is flammable, with a flash point of 54 °C (129.2 °F).
How is 2-(Trifluoromethoxy)aniline shipped and exported?
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As a global supplier, Tech Serve Solutions is experienced in exporting chemicals like 2-(Trifluoromethoxy)aniline, adhering to all relevant international shipping and dangerous goods regulations (UN 1993, Class 3, Packing Group III).
How can I request a quote or sample?
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To request a quote or sample of 2-(Trifluoromethoxy)aniline, please contact our sales team through the website or direct inquiry channels.
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