2-(Trifluoroacetoxy)pyridine
2-(Trifluoroacetoxy)pyridine (CAS: 96254-05-6; Formula: C7H4F3NO2) is a fluorinated pyridine derivative with a molecular weight of 191.11 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly for introducing the 2-pyridyl moiety with a trifluoroacetoxy leaving group. It is primarily utilised in chemical research and development for the construction of more complex heterocyclic compounds.
- IUPAC
- 2-Pyridyl trifluoroacetate
- Synonyms
- 2-Pyridyl trifluoroacetate
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of novel organic molecules and complex heterocyclic structures. Its reactive trifluoroacetoxy group facilitates various coupling and substitution reactions.
Pharmaceutical Research
Serves as a building block in the development of new pharmaceutical agents. The incorporation of fluorinated pyridine rings can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Material Science
May be employed in the synthesis of specialised materials where a fluorinated pyridine unit is required to impart specific electronic or physical properties.
| Molecular weight | 191.11 |
|---|---|
| Empirical formula | C7H4F3NO2 |
| Assay | ≥98.0% |
| Boiling point | 60 °C/0.3 mmHg(lit.) |
| Density | 1.356 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.421(lit.)n20/D 1.422 |
| Storage temperature | 2-8°C |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 50 °C / 122 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoroacetoxy)pyridine used for?
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2-(Trifluoroacetoxy)pyridine is primarily used as a building block and intermediate in organic synthesis, particularly for the development of novel pharmaceutical agents and specialised materials.
What is the CAS number and chemical formula for 2-(Trifluoroacetoxy)pyridine?
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The CAS number is 96254-05-6 and the empirical formula (Hill notation) is C7H4F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoroacetoxy)pyridine with an assay of ≥98.0%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should 2-(Trifluoroacetoxy)pyridine be handled safely?
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2-(Trifluoroacetoxy)pyridine is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and respiratory protection. Store in a cool, well-ventilated area away from heat and ignition sources.
Is 2-(Trifluoroacetoxy)pyridine a controlled substance?
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The provided data does not indicate that 2-(Trifluoroacetoxy)pyridine is a controlled substance.
How is 2-(Trifluoroacetoxy)pyridine packed and shipped?
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2-(Trifluoroacetoxy)pyridine is shipped according to relevant transport regulations (UN 1993, Class 3, Packing Group III). Specific packing details are available upon request.
How can I request a sample or quote for 2-(Trifluoroacetoxy)pyridine?
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To request a sample or quote, please contact our sales department through the website or provide your details via the enquiry form.
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