2-Fluorobiphenyl-4-carboxylic acid
2-Fluorobiphenyl-4-carboxylic acid (CAS: 137045-30-8) is a fluorinated organic building block with the molecular formula FC6H3(C6H5)CO2H and a molecular weight of 216.21 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly for the construction of complex molecules. Its structure, featuring a fluorinated biphenyl core with a carboxylic acid group, makes it useful in the development of pharmaceuticals, agrochemicals, and advanced materials.

Pharmaceutical Intermediate
Utilised in the synthesis pathways for novel drug candidates and active pharmaceutical ingredients (APIs). The fluorinated biphenyl moiety can influence pharmacokinetic properties.
Agrochemical Synthesis
Incorporated into the development of new crop protection agents. Fluorine atoms can enhance the biological activity and stability of agrochemicals.
Materials Science
Serves as a building block for functional organic materials, potentially impacting polymers, liquid crystals, or organic electronics.
Research and Development
A versatile reagent for academic and industrial research labs exploring new chemical entities and synthetic methodologies.
| Molecular weight | 216.21 |
|---|---|
| Linear formula | FC6H3(C6H5)CO2H |
| Assay | 97% |
| Melting point | 223-227 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorobiphenyl-4-carboxylic acid used for?
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2-Fluorobiphenyl-4-carboxylic acid is primarily used as an intermediate in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials. It is also a valuable reagent for general chemical research.
What are the CAS number and chemical formula for 2-Fluorobiphenyl-4-carboxylic acid?
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The CAS number is 137045-30-8, and the chemical formula is FC6H3(C6H5)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluorobiphenyl-4-carboxylic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Fluorobiphenyl-4-carboxylic acid be handled safely?
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This compound is a warning irritant, harmful if swallowed, and causes skin and serious eye irritation, and may cause respiratory irritation (H302, H315, H319, H335). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), should be worn. Handle in a well-ventilated area.
Can Tech Serve Solutions export 2-Fluorobiphenyl-4-carboxylic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for 2-Fluorobiphenyl-4-carboxylic acid?
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Please contact our sales department via the website or direct email to request a sample or a quotation.
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