2-Fluorobiphenyl
2-Fluorobiphenyl (CAS: 321-60-8), with the molecular formula C<sub>6</sub>H<sub>5</sub>C<sub>6</sub>H<sub>4</sub>F and a molecular weight of 172.20 g/mol, is an organic fluorinated building block. It is a valuable intermediate in organic synthesis, particularly within the fields of pharmaceutical research and materials science. Its structure, featuring a fluorine atom on one phenyl ring of a biphenyl system, allows for specific reactivity and electronic properties essential for developing novel compounds.

Pharmaceutical Intermediates
2-Fluorobiphenyl serves as a key building block in the synthesis of complex organic molecules with potential pharmaceutical applications. Its fluorinated biphenyl structure can be incorporated into drug candidates to modify properties such as metabolic stability and binding affinity.
Materials Science
This compound finds use in the development of advanced materials, including liquid crystals and organic electronic components. The introduction of fluorine can influence the optoelectronic characteristics and thermal stability of polymers and organic semiconductors.
Organic Synthesis Reagent
As a versatile aryl halide, 2-Fluorobiphenyl is employed in various cross-coupling reactions and other transformations. It enables the introduction of the fluorobiphenyl moiety into larger molecular architectures for diverse research purposes.
| Molecular weight | 172.20 |
|---|---|
| Linear formula | C6H5C6H4F |
| Assay | ≥98.0% (GC) |
| Grade | purum |
| Boiling point | 248 °C(lit.) |
| Melting point | 71-74 °C(lit.)71-74 °C |



Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-37/38-41-50/53 |
| Safety statements (S) | 26-39-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorobiphenyl used for?
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2-Fluorobiphenyl is primarily used as a building block in organic synthesis, particularly for developing pharmaceutical intermediates and advanced materials. Its fluorinated biphenyl structure is valuable for modifying molecular properties in research and development.
What is the CAS number and chemical formula for 2-Fluorobiphenyl?
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The CAS number for 2-Fluorobiphenyl is 321-60-8, and its chemical formula is C<sub>6</sub>H<sub>5</sub>C<sub>6</sub>H<sub>4</sub>F.
What grade and purity does Tech Serve Solutions supply for 2-Fluorobiphenyl?
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Tech Serve Solutions supplies 2-Fluorobiphenyl with a grade of 'purum' and an assay of ≥98.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia standard unless explicitly stated.
How should 2-Fluorobiphenyl be handled safely?
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2-Fluorobiphenyl is classified as dangerous. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), may cause respiratory irritation (H335), and is very toxic to aquatic life with long-lasting effects (H410). Handle with appropriate personal protective equipment in a well-ventilated area, and avoid release to the environment. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is 2-Fluorobiphenyl packed and exported by TSS?
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Tech Serve Solutions packs and exports 2-Fluorobiphenyl adhering to all relevant shipping regulations, including UN 3077 for environmentally hazardous substances. Packaging is designed to ensure product integrity and safety during transit, and we cater to global export requirements.
How can I request a quote or sample for 2-Fluorobiphenyl?
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To request a quote or sample for 2-Fluorobiphenyl, please contact our sales team via the website or listed contact details, providing your specific requirements and delivery information.
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