2-Fluorobenzyl chloride
2-Fluorobenzyl chloride (CAS: 345-35-7, Formula: FC6H4CH2Cl) is a halogenated aromatic organic compound with a molecular weight of 144.57 g/mol. As a fluorinated building block, it serves as a versatile intermediate in organic synthesis. Its applications are primarily in the development of new chemical entities and for further functionalisation in research and industrial chemical processes. TSS supplies this compound for your chemical synthesis needs.
- IUPAC
- α-Chloro-2-fluorotoluene,1-Chloromethyl-2-fluorobenzene

Intermediate in Organic Synthesis
2-Fluorobenzyl chloride is a valuable precursor for introducing the 2-fluorobenzyl moiety into various organic molecules. It participates in nucleophilic substitution reactions, enabling the construction of more complex chemical structures.
Pharmaceutical and Agrochemical Research
This compound is utilized in the research and development of novel pharmaceutical and agrochemical agents. The presence of fluorine can significantly alter the physicochemical and biological properties of target molecules.
Building Block for Fluorinated Compounds
As a member of the fluorinated building blocks category, 2-Fluorobenzyl chloride is essential for chemists synthesising speciality chemicals where fluorine incorporation is desired for specific performance characteristics.
| Molecular weight | 144.57 |
|---|---|
| Linear formula | FC6H4CH2Cl |
| Assay | 98% |
| Boiling point | 86 °C/40 mmHg(lit.) |
| Density | 1.216 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.514(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 57 °C / 134.6 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorobenzyl chloride used for?
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2-Fluorobenzyl chloride is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceutical and agrochemical compounds, and as a building block for other fluorinated organic molecules.
What is the CAS number and formula for 2-Fluorobenzyl chloride?
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The CAS number for 2-Fluorobenzyl chloride is 345-35-7, and its molecular formula is FC6H4CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluorobenzyl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Fluorobenzyl chloride be handled safely?
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2-Fluorobenzyl chloride is a danger. It is flammable and causes severe skin burns and eye damage (H226-H314). Handle with appropriate personal protective equipment including gloves, goggles, and face shields, and ensure adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.
Is 2-Fluorobenzyl chloride flammable?
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Yes, 2-Fluorobenzyl chloride is flammable, with a flash point of 57 °C (134.6 °F).
How is 2-Fluorobenzyl chloride packed and exported?
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2-Fluorobenzyl chloride is packed and exported according to international shipping regulations for hazardous materials, including UN 2920, Class 3(8), Packing Group II.
How can I request a quote or sample for 2-Fluorobenzyl chloride?
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To request a quote or sample for 2-Fluorobenzyl chloride, please contact our sales team via the website or by phone, providing your specific requirements.
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