2-Fluorobenzoyl chloride
2-Fluorobenzoyl chloride (CAS: 393-52-2) is an organohalogen compound with the linear formula FC<sub>6</sub>H<sub>4</sub>COCl and a molecular weight of 158.56 g/mol. As an acid halide, it serves as a reactive intermediate in organic synthesis. Its fluorinated aromatic structure makes it a valuable building block for the construction of more complex molecules, particularly in the pharmaceutical and agrochemical industries. This compound is supplied by Tech Serve Solutions.
Pharmaceutical Intermediate
2-Fluorobenzoyl chloride is utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its reactivity allows for the introduction of the 2-fluorobenzoyl moiety into complex molecular scaffolds.
Agrochemical Synthesis
This compound acts as a building block in the development of novel pesticides, herbicides, and fungicides. The incorporation of fluorine can enhance the biological activity and stability of agrochemical products.
Material Science Research
It finds application in the creation of specialised polymers and advanced materials where the presence of a fluorinated aromatic group imparts unique properties. Research laboratories utilise it for developing new functional materials.
Organic Synthesis Reagent
As a versatile acylating agent, 2-Fluorobenzoyl chloride is employed in various organic transformations. It is used to introduce the 2-fluorobenzoyl group onto alcohols, amines, and other nucleophiles.
| Molecular weight | 158.56 |
|---|---|
| Linear formula | FC6H4COCl |
| Assay | ≥98.0% (GC) |
| Grade | purum |
| Boiling point | 90-92 °C/15 mmHg(lit.) |
| Density | 1.328 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.536(lit.)n20/D 1.536 |
| Melting point | 4 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 122 °C / 251.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorobenzoyl chloride used for?
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2-Fluorobenzoyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly for the production of pharmaceuticals, agrochemicals, and specialised materials.
What are the CAS number and formula for 2-Fluorobenzoyl chloride?
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The CAS number is 393-52-2 and the linear formula is FC<sub>6</sub>H<sub>4</sub>COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluorobenzoyl chloride at a purity of ≥98.0% (GC) with a 'purum' grade. We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with 2-Fluorobenzoyl chloride?
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2-Fluorobenzoyl chloride is classified as Danger, with hazard statements H314 (Causes severe skin burns and eye damage) and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, is essential during handling.
How is 2-Fluorobenzoyl chloride packed and shipped by TSS?
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Tech Serve Solutions exports 2-Fluorobenzoyl chloride globally, adhering to all relevant shipping regulations for hazardous materials (UN 3265, Class 8, Packing Group II).
How can I request a quote or sample for 2-Fluorobenzoyl chloride?
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To request a quote or sample, please contact our sales team via the website or direct email, providing your specific requirements and shipping details.
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