2-Fluorobenzonitrile
2-Fluorobenzonitrile (CAS 394-47-8, FC6H4CN) is a valuable fluorinated aromatic compound with a molecular weight of 121.11 g/mol. This chemical serves as a key building block in organic synthesis, particularly for introducing fluorinated phenyl groups into more complex molecules. Its utility spans various research and development sectors, including the pharmaceutical and agrochemical industries. Tech Serve Solutions offers this high-purity reagent for demanding chemical applications.
Synthesis of Heterocyclic Compounds
2-Fluorobenzonitrile is employed in the synthesis of diverse heterocyclic structures. For example, it has been utilised in the preparation of 3-amino-1,2-benzisoxazoles and related derivatives, which are important scaffolds in medicinal chemistry.
Precursor for Tetrazole Derivatives
This compound acts as a precursor in the synthesis of tetrazole rings. It has been documented for its use in preparing substituted tetrazoles, such as 5-(4′-methyl [1, 1′-biphenyl]-2-yl)-1H-tetrazole.
Intermediate in Organic Synthesis
As a versatile building block, 2-Fluorobenzonitrile facilitates the construction of complex organic molecules. Its reactivity allows for diverse transformations, contributing to the development of novel compounds for research purposes.
Xanthone-Iminium Triflate Synthesis
Research indicates the use of 2-Fluorobenzonitrile in the preparation of xanthone-iminium triflates, which may find applications in materials science or as specialised reagents.
| Molecular weight | 121.11 |
|---|---|
| Linear formula | FC6H4CN |
| Assay | ≥98.0% (GC) |
| Boiling point | 90 °C/21 mmHg(lit.) |
| Density | 1.116 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.505(lit.)n20/D 1.505 |
| Application | 2-Fluorobenzonitrile was used in the synthesis of :• 3-amino-1,2-benzisoxazoles1• 6-(acetylaminomethyl)-3-amino-1,2-benzisoxazole1• 5-(4′-methyl [1, 1′-biphenyl]-2-yl)-1H-tetrazole2• xanthone-iminium triflates3 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorobenzonitrile used for?
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2-Fluorobenzonitrile is primarily used as a building block in organic synthesis for creating more complex molecules, including heterocyclic compounds like 3-amino-1,2-benzisoxazoles and tetrazole derivatives.
What are the CAS number and formula for 2-Fluorobenzonitrile?
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The CAS number for 2-Fluorobenzonitrile is 394-47-8, and its linear formula is FC6H4CN.
What grade and purity does Tech Serve Solutions supply for 2-Fluorobenzonitrile?
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Tech Serve Solutions supplies 2-Fluorobenzonitrile with a purity of ≥98.0% (GC). This is a technical/research grade, and TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
What are the safety considerations when handling 2-Fluorobenzonitrile?
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2-Fluorobenzonitrile is classified as Danger (GHS05, GHS07). It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including safety goggles, face shields, gloves, and suitable respiratory protection, is essential. Ensure adequate ventilation and handle with care.
Is 2-Fluorobenzonitrile a controlled substance?
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Based on the provided data, there is no indication that 2-Fluorobenzonitrile (CAS 394-47-8) is a controlled substance. However, users should always verify local regulations.
How is 2-Fluorobenzonitrile packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals in compliance with all relevant national and international regulations for hazardous materials, ensuring safe and secure transit.
How can I request a sample or quote for 2-Fluorobenzonitrile?
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To request a sample or obtain a quote for 2-Fluorobenzonitrile, please contact our sales team through the dedicated enquiry form on our website or by calling our customer service line.
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