2-Fluorobenzenesulfonyl chloride
2-Fluorobenzenesulfonyl chloride (CAS: 2905-21-7, Formula: FC6H4SO2Cl, Molar Mass: 194.61 g/mol) is a valuable organosulfur compound. As a sulfonyl halide and a fluorinated aromatic, it serves as a versatile building block in organic synthesis. Its reactivity makes it useful for introducing the 2-fluorobenzenesulfonyl group into various organic molecules, finding applications in the development of pharmaceuticals and agrochemicals.
Organic Synthesis Reagent
2-Fluorobenzenesulfonyl chloride acts as an electrophilic reagent for the synthesis of sulfonamides, sulfonates, and other sulfur-containing organic compounds. It is frequently employed in the construction of complex molecular architectures.
Pharmaceutical Intermediate
This compound is utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). The presence of both the fluorine atom and the sulfonyl chloride group allows for targeted modifications in drug discovery programmes.
Agrochemical Development
Its structural features make 2-Fluorobenzenesulfonyl chloride a useful intermediate in the synthesis of novel pesticides and herbicides. The incorporation of fluorinated aromatic moieties can influence the biological activity and metabolic stability of agrochemicals.
| Molecular weight | 194.61 |
|---|---|
| Linear formula | FC6H4SO2Cl |
| Assay | 97% |
| Boiling point | 246-247 °C(lit.) |
| Density | 1.47 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.537(lit.) |
| Melting point | 27-30 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorobenzenesulfonyl chloride used for?
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2-Fluorobenzenesulfonyl chloride is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It serves to introduce the 2-fluorobenzenesulfonyl group into target molecules.
What is the CAS number and molecular formula for 2-Fluorobenzenesulfonyl chloride?
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The CAS number for 2-Fluorobenzenesulfonyl chloride is 2905-21-7, and its molecular formula is FC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply for 2-Fluorobenzenesulfonyl chloride?
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Tech Serve Solutions supplies 2-Fluorobenzenesulfonyl chloride with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for 2-Fluorobenzenesulfonyl chloride?
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2-Fluorobenzenesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, face shield, and respiratory protection, must be used. It is corrosive and should be handled with extreme care in a well-ventilated area.
How is 2-Fluorobenzenesulfonyl chloride packed, shipped, and exported?
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2-Fluorobenzenesulfonyl chloride is packed in compliance with international shipping regulations for hazardous materials. It is shipped globally by Tech Serve Solutions, a trusted exporter of fine chemicals and reagents.
How can I request a sample or a quote for 2-Fluorobenzenesulfonyl chloride?
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To request a sample or a quote for 2-Fluorobenzenesulfonyl chloride, please contact our sales department through the TSS website or via direct inquiry.
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