[2-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution
[2-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution (CAS 480424-80-4), with the linear formula C6H4CH2NC4H8MgBr and a molecular weight of 264.44 g/mol, is a Grignard reagent. Supplied as a 0.25 M solution in THF, it is primarily utilised in organic synthesis for carbon-carbon bond formation and the introduction of aryl groups. Its reactivity makes it a valuable tool in the development of complex molecules within research and chemical manufacturing.
![[2-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution (C6H4CH2NC4H8MgBr) — chemical structure, CAS 480424-80-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480424-80-4.png&w=3840&q=75)
Organic Synthesis Reagent
As a Grignard reagent, it facilitates nucleophilic addition to carbonyl compounds and other electrophiles, enabling the construction of new carbon-carbon bonds essential for complex molecule synthesis.
Aryl Group Introduction
This organometallic compound serves as an effective agent for introducing the 2-(1-pyrrolidinylmethyl)phenyl moiety into organic structures through various coupling reactions.
Pharmaceutical Intermediate Synthesis
Its utility extends to the synthesis of advanced intermediates for the pharmaceutical industry, where precise functional group manipulation is critical.
| Molecular weight | 264.44 |
|---|---|
| Linear formula | C6H4CH2NC4H8MgBr |
| Boiling point | 65 °C |
| Density | 0.919 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [2-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution used for?
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This compound is used as a Grignard reagent in organic synthesis, primarily for forming carbon-carbon bonds and introducing aryl groups into molecules. It is particularly useful in the synthesis of complex organic structures and pharmaceutical intermediates.
What is the CAS number and formula for this compound?
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The CAS number is 480424-80-4. The linear formula is C6H4CH2NC4H8MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a 0.25 M solution in Tetrahydrofuran (THF). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, or EP grade.
How should [2-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution be handled?
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This is a highly flammable liquid and vapour (H225), causing severe skin burns and eye damage (H314), and may cause respiratory irritation (H335). It can also cause cancer (H351). Handle with extreme care in a well-ventilated area, avoiding heat, sparks, and open flames. It reacts violently with water and may form explosive peroxides. Always use appropriate personal protective equipment and follow strict safety protocols.
How is this chemical packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures that [2-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution is appropriately packed according to international shipping regulations, including UN 2924, Class 8(3), Packing Group II, for safe transit worldwide.
How can I request a sample or quote?
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To request a sample or a quotation for [2-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution, please contact our sales team through the TSS website or direct email, providing your specific requirements.
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