4-Chloroaniline
4-Chloroaniline (CAS: 106-47-8), with the chemical formula ClC6H4NH2 and a molecular weight of 127.57 g/mol, is an aromatic amine. It appears as a crystalline solid. This compound serves as a critical building block in organic synthesis and is utilised in the production of various chemical compounds, including dyes and pharmaceuticals. It is primarily supplied for research and industrial applications.
- Synonyms
- p-Chloroaniline4-AminochlorobenzeneAniline, 4-chloro-Benzeneamine, 4-chloro-1-Amino-4-chlorobenzene4-Chlorobenzenaminep-Anidinium chloride

Dye Synthesis Intermediate
4-Chloroaniline is employed in the synthesis of azo dyes and other colorants. Its structure provides a reactive site for coupling reactions, contributing to the formation of vibrant and stable dyes.
Pharmaceutical Precursor
This compound acts as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its incorporation into molecular structures is essential for creating specific therapeutic agents.
Agrochemical Intermediate
It can be used in the manufacturing process of certain pesticides and herbicides. The chloroaniline moiety is a key component in the development of crop protection chemicals.
Organic Synthesis Building Block
As a versatile organic building block, 4-Chloroaniline is used in a wide range of chemical transformations for creating complex molecules in research and development.
| Molecular weight | 127.57 |
|---|---|
| Linear formula | ClC6H4NH2 |
| Assay | ≥99% |
| Boiling point | 232 °C(lit.) |
| Vapour pressure | 0.15 mmHg (25 °C) |
| Vapour density | 4.4 (vs air) |
| Melting point | 67-70 °C(lit.) |



Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H317May cause an allergic skin reaction
- H331Toxic if inhaled
- H350May cause cancer
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 120 °C / 248 °F |
| Transport (UN / ADR) | UN 2018 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 45-23/24/25-43-50/53 |
| Safety statements (S) | 53-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Purified By | sublimation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloroaniline used for?
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4-Chloroaniline is used as an intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals, and as a general building block in organic synthesis.
What is the CAS number and chemical formula for 4-Chloroaniline?
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The CAS number for 4-Chloroaniline is 106-47-8, and its chemical formula is ClC6H4NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloroaniline with a purity of ≥99%. This product is supplied for laboratory and industrial use and is not represented as USP, BP, EP, or any pharmacopoeia grade.
How should 4-Chloroaniline be handled safely?
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4-Chloroaniline is a toxic and hazardous substance. It is harmful if swallowed, in contact with skin, or if inhaled, and can cause an allergic skin reaction and may cause cancer. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3), must be used. Handle only in a well-ventilated area and avoid release to the environment.
Is 4-Chloroaniline a controlled substance?
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The provided data does not indicate that 4-Chloroaniline is a controlled substance. However, users should consult local regulations regarding its handling and use.
How is 4-Chloroaniline packed and shipped?
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4-Chloroaniline is packed and shipped according to international regulations for hazardous materials. It is classified under UN 2018, Hazard Class 6.1, Packing Group II.
How can I request a sample or quote for 4-Chloroaniline?
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To request a sample or a quote for 4-Chloroaniline, please contact our sales team via the website or direct inquiry channels.
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