[2-(1-Piperidinylmethyl)phenyl]magnesium bromide solution
[2-(1-Piperidinylmethyl)phenyl]magnesium bromide solution (CAS: 480424-81-5) is an organometallic reagent with the linear formula C <sub>6</sub>H <sub>4</sub>CH <sub>2</sub>NC <sub>5</sub>H <sub>10</sub>MgBr and a molecular weight of 278.47 g/mol. Supplied as a 0.25 M solution in THF, this compound is valuable in organic synthesis for introducing specific aryl functionalities. It is a reactive Grignard reagent requiring careful handling due to its flammability and corrosive properties.
![[2-(1-Piperidinylmethyl)phenyl]magnesium bromide solution (C6H4CH2NC5H10MgBr) — chemical structure, CAS 480424-81-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480424-81-5.png&w=3840&q=75)
Organometallic Synthesis
As a Grignard reagent, it is employed in nucleophilic addition reactions to carbonyl compounds and other electrophiles, facilitating carbon-carbon bond formation in complex molecule synthesis.
Aryl Functionalization
This reagent allows for the direct introduction of the 2-(1-piperidinylmethyl)phenyl group onto various organic scaffolds, enabling the construction of specialized molecular architectures.
Chemical Research
Utilised in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities.
| Molecular weight | 278.47 |
|---|---|
| Linear formula | C6H4CH2NC5H10MgBr |
| Boiling point | 65 °C |
| Density | 0.922 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [2-(1-Piperidinylmethyl)phenyl]magnesium bromide solution used for?
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This compound is primarily used as an organometallic reagent in organic synthesis for forming carbon-carbon bonds and introducing aryl functionalities.
What are the CAS number and formula for this product?
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The CAS number is 480424-81-5 and the linear formula is C <sub>6</sub>H <sub>4</sub>CH <sub>2</sub>NC <sub>5</sub>H <sub>10</sub>MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a 0.25 M solution in THF. We do not represent this product as USP, BP, or EP grade.
How should this chemical be handled?
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This is a Danger substance that is highly flammable (H225), causes severe skin burns and eye damage (H314), and may cause respiratory irritation (H335). It may also be suspected of causing cancer (H351). Handle with extreme caution in a well-ventilated area, away from ignition sources, and avoid contact with water due to violent reaction. Refer to the Safety Data Sheet for full handling protocols.
Is this product available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or a quotation for this product.
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