2-Fluorobenzylzinc chloride solution
2-Fluorobenzylzinc chloride solution (CAS: 312693-05-3) is an organozinc halide reagent with the linear formula FC₆H₄CH₂ZnCl and a molecular weight of 209.96. Supplied as a 0.5 M solution in THF, this compound is primarily utilised as a versatile building block in organic synthesis. Its reactive nature makes it valuable for carbon-carbon bond formation, particularly in cross-coupling reactions, enabling the construction of complex fluorinated organic molecules for research and development.
Organometallic Synthesis
Serves as a key reagent in organometallic chemistry for introducing the 2-fluorobenzyl group into organic molecules. It is particularly useful in cross-coupling reactions such as Negishi coupling.
Fluorinated Compound Synthesis
Facilitates the synthesis of complex organic molecules containing a fluorine atom, which are of interest in pharmaceutical and agrochemical research due to fluorine's unique electronic properties.
Pharmaceutical Intermediates
Used in the multi-step synthesis of advanced pharmaceutical intermediates, where precise introduction of fluorinated benzyl moieties is required.
Materials Science
Applicable in the development of novel materials where fluorinated organic components can impart specific properties like hydrophobicity or altered electronic characteristics.
| Molecular weight | 209.96 |
|---|---|
| Linear formula | FC6H4CH2ZnCl |
| Density | 0.97 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorobenzylzinc chloride solution used for?
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2-Fluorobenzylzinc chloride solution is used in organic synthesis, particularly for carbon-carbon bond formation via cross-coupling reactions, and for the synthesis of fluorinated organic compounds and pharmaceutical intermediates.
What is the CAS number and formula for 2-Fluorobenzylzinc chloride solution?
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The CAS number is 312693-05-3 and the linear formula is FC₆H₄CH₂ZnCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluorobenzylzinc chloride solution at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, or EP grade; it is supplied for research and laboratory use.
How should 2-Fluorobenzylzinc chloride solution be handled and stored?
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This compound is flammable and may form explosive peroxides. Store at 2-8°C, away from ignition sources. Handle in a well-ventilated area with appropriate personal protective equipment (gloves, eye protection) to avoid skin, eye, and respiratory irritation. Refer to the Safety Data Sheet (SDS) for detailed handling procedures.
Is 2-Fluorobenzylzinc chloride solution available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. Please contact our sales team for export inquiries and to arrange shipment.
How can I request a sample or a quote for 2-Fluorobenzylzinc chloride solution?
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To request a sample or a quotation, please visit the product page on our website and use the designated 'Request Sample' or 'Request Quote' functions, or contact our customer service department directly.
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