Valdecoxib
Valdecoxib (CAS: 181695-72-7; C16H14N2O3S) is a selective cyclooxygenase-2 (COX-2) inhibitor. This compound, with a molecular weight of 314.36 g/mol, is primarily recognised for its anti-inflammatory and analgesic properties. It functions by inhibiting the COX-2 enzyme, a key mediator in the inflammatory pathway. Valdecoxib is utilised in research settings for studying inflammation, pain mechanisms, and related biochemical processes.
- IUPAC
- 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
- Synonyms
- 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
COX-2 Inhibition Studies
Valdecoxib serves as a selective COX-2 inhibitor for biochemical research. It is used to investigate the role of COX-2 in various physiological and pathological processes, including inflammation and pain signalling.
Inflammation Research
As a compound that targets the arachidonic acid cascade, Valdecoxib is employed in studies aimed at understanding the molecular mechanisms of inflammation. Its selective action allows for targeted investigation of COX-2 pathways.
Pharmacological Research Tool
This compound acts as a valuable tool in pharmacological research for evaluating the effects and mechanisms of COX-2 inhibition in cellular and potentially in vitro systems.
| Molecular weight | 314.36 |
|---|---|
| Empirical formula | C16H14N2O3S |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: >25 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H361D
- H373May cause damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P281Use personal protective equipment as required
- P501Dispose of contents and container per local regulations
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 63-48/22-51/53 |
| Safety statements (S) | 36/37-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Valdecoxib used for?
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Valdecoxib is used in research as a selective cyclooxygenase-2 (COX-2) inhibitor to study inflammation and pain mechanisms. It is also a reference compound in biochemical and pharmacological research.
What is the CAS number and chemical formula for Valdecoxib?
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The CAS number for Valdecoxib is 181695-72-7, and its chemical formula is C16H14N2O3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Valdecoxib with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should Valdecoxib be handled and stored?
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Valdecoxib is classified with GHS08 and GHS09 symbols, a Warning signal word, and carries hazard statements H361d (Suspected of damaging fertility or the unborn child) and H373 (May cause damage to organs through prolonged or repeated exposure), and H410 (Very toxic to aquatic life with long lasting effects). It requires careful handling to avoid exposure and should be stored at room temperature.
Is Valdecoxib a controlled substance?
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The provided data does not indicate that Valdecoxib is a controlled substance.
How are Valdecoxib products packed and shipped?
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Valdecoxib is typically supplied as a white to off-white powder and is packed and exported according to standard fine chemical procedures to ensure product integrity and safety during transit.
How can I request a sample or quote for Valdecoxib?
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To request a sample or a quote for Valdecoxib, please contact the Tech Serve Solutions sales department through our official website or registered contact channels.
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