2-Fluoroethyl chloroformate
2-Fluoroethyl chloroformate (CAS: 462-27-1) is a fluorinated organic compound with the linear formula ClCO₂CH₂CH₂F and a molecular weight of 126.51 g/mol. This acid halide serves as a valuable building block in organic synthesis, particularly for introducing the 2-fluoroethoxycarbonyl group. It is employed in the preparation of various chemical intermediates and specialised organic compounds.

Organic Synthesis Building Block
2-Fluoroethyl chloroformate is utilised as a reactive intermediate in complex organic syntheses. Its structure allows for the incorporation of a fluoroethyl moiety into target molecules, making it useful for creating novel compounds.
Reagent for Derivatisation
This compound can be employed as a derivatisation reagent, particularly in analytical chemistry, to modify analytes for improved detection or separation. Its reactivity is suitable for converting functional groups in preparation for techniques like HPLC.
Fluorinated Compound Precursor
As a source of the 2-fluoroethoxycarbonyl group, it is instrumental in synthesising a range of fluorinated organic molecules. These fluorinated compounds often exhibit unique chemical and physical properties beneficial in various industries.
| Molecular weight | 126.51 |
|---|---|
| Linear formula | ClCO2CH2CH2F |
| Assay | 97% |
| Boiling point | 131-135 °C(lit.) |
| Density | 1.34 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4(lit.) |
| Vapour pressure | 0.83 mmHg (20 °C) |
| Storage temperature | 2-8°C |



Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 2742 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23-34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoroethyl chloroformate used for?
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2-Fluoroethyl chloroformate is primarily used as a building block in organic synthesis and as a derivatisation reagent for analytical purposes. It allows for the introduction of the 2-fluoroethoxycarbonyl group into various molecules.
What is the CAS number and formula for 2-Fluoroethyl chloroformate?
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The CAS number for 2-Fluoroethyl chloroformate is 462-27-1, and its linear formula is ClCO₂CH₂CH₂F.
What grade and purity does Tech Serve Solutions supply for 2-Fluoroethyl chloroformate?
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Tech Serve Solutions supplies 2-Fluoroethyl chloroformate with a purity of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Fluoroethyl chloroformate be handled safely?
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2-Fluoroethyl chloroformate is a hazardous substance classified as Danger. It is flammable, causes severe skin burns and eye damage, and is toxic if inhaled. Handling requires appropriate personal protective equipment including gloves, goggles, face shield, and a suitable respirator. Store in a cool, well-ventilated area at 2-8°C.
How is 2-Fluoroethyl chloroformate packed, shipped, and exported?
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Information regarding specific packing, shipping, and export details for 2-Fluoroethyl chloroformate can be obtained by contacting our sales department directly. We adhere to all relevant regulations for the safe transport of hazardous chemicals.
How can I request a quote or sample of 2-Fluoroethyl chloroformate?
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To request a quote or a sample of 2-Fluoroethyl chloroformate, please contact our sales team via the provided channels on our website. We will be pleased to assist you with your inquiry.
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