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2-Fluoroethyl chloroformate

CAS 462-27-1ClCO2CH2CH2FChemical Synthesis

2-Fluoroethyl chloroformate (CAS: 462-27-1) is a fluorinated organic compound with the linear formula ClCO₂CH₂CH₂F and a molecular weight of 126.51 g/mol. This acid halide serves as a valuable building block in organic synthesis, particularly for introducing the 2-fluoroethoxycarbonyl group. It is employed in the preparation of various chemical intermediates and specialised organic compounds.

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2-Fluoroethyl chloroformate (ClCO2CH2CH2F) — chemical structure, CAS 462-27-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Acid HalidesAnalytical ReagentsAnalytical/ChromatographyBuilding BlocksCarbonyl ChloridesCarbonyl CompoundsChemical SynthesisDerivatization ReagentsDerivatization Reagents HPLCFluorescence
01 /Applications

Organic Synthesis Building Block

2-Fluoroethyl chloroformate is utilised as a reactive intermediate in complex organic syntheses. Its structure allows for the incorporation of a fluoroethyl moiety into target molecules, making it useful for creating novel compounds.

Reagent for Derivatisation

This compound can be employed as a derivatisation reagent, particularly in analytical chemistry, to modify analytes for improved detection or separation. Its reactivity is suitable for converting functional groups in preparation for techniques like HPLC.

Fluorinated Compound Precursor

As a source of the 2-fluoroethoxycarbonyl group, it is instrumental in synthesising a range of fluorinated organic molecules. These fluorinated compounds often exhibit unique chemical and physical properties beneficial in various industries.

02 /Properties
Molecular weight126.51
Linear formulaClCO2CH2CH2F
Assay97%
Boiling point131-135 °C(lit.)
Density1.34 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.4(lit.)
Vapour pressure0.83 mmHg (20 °C)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H226Flammable liquid and vapour
  • H314Causes severe skin burns and eye damage
  • H331Toxic if inhaled

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point58 °C / 136.4 °F
Transport (UN / ADR)UN 2742 6.1/PG 2
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)23-34
Safety statements (S)26-27-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
462-27-1
MDL number
MFCD01726287
PubChem substance
24874472
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Fluoroethyl chloroformate used for?

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2-Fluoroethyl chloroformate is primarily used as a building block in organic synthesis and as a derivatisation reagent for analytical purposes. It allows for the introduction of the 2-fluoroethoxycarbonyl group into various molecules.

What is the CAS number and formula for 2-Fluoroethyl chloroformate?

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The CAS number for 2-Fluoroethyl chloroformate is 462-27-1, and its linear formula is ClCO₂CH₂CH₂F.

What grade and purity does Tech Serve Solutions supply for 2-Fluoroethyl chloroformate?

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Tech Serve Solutions supplies 2-Fluoroethyl chloroformate with a purity of 97%. We do not represent this product as USP, BP, or EP grade.

How should 2-Fluoroethyl chloroformate be handled safely?

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2-Fluoroethyl chloroformate is a hazardous substance classified as Danger. It is flammable, causes severe skin burns and eye damage, and is toxic if inhaled. Handling requires appropriate personal protective equipment including gloves, goggles, face shield, and a suitable respirator. Store in a cool, well-ventilated area at 2-8°C.

How is 2-Fluoroethyl chloroformate packed, shipped, and exported?

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Information regarding specific packing, shipping, and export details for 2-Fluoroethyl chloroformate can be obtained by contacting our sales department directly. We adhere to all relevant regulations for the safe transport of hazardous chemicals.

How can I request a quote or sample of 2-Fluoroethyl chloroformate?

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To request a quote or a sample of 2-Fluoroethyl chloroformate, please contact our sales team via the provided channels on our website. We will be pleased to assist you with your inquiry.

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