2-Fluoroiodobenzene
2-Fluoroiodobenzene (CAS: 348-52-7), a halogenated aromatic compound with the formula FC6H4I and a molecular weight of 222.00 g/mol, is a key building block in organic synthesis. Its unique structure, featuring both fluorine and iodine substituents on a benzene ring, makes it valuable for introducing fluorinated aryl moieties. This compound is primarily employed in research and development for the synthesis of complex organic molecules, pharmaceuticals, and advanced materials.
Synthesis of Bridged Biphenyl Compounds
2-Fluoroiodobenzene has been utilised in the synthesis of bridged biphenyl compounds. Examples include the preparation of 1-fluoro-8-methylbiphenylenes and 4-fluoro-5-methylfluorenes, demonstrating its utility in constructing polycyclic aromatic systems.
Precursor for Benzothiophene Derivatives
This compound serves as a precursor in the synthesis of specific benzothiophene derivatives. It was used in the preparation of 2-acetyl-7-iodo-1-benzothiophene, highlighting its role in heterocyclic chemistry.
Preparation of Chiral Sulfoxides
2-Fluoroiodobenzene is employed in the synthesis of chiral ortho-phosphanophenyl sulfoxides. This application underscores its importance in asymmetric synthesis and the creation of stereochemically defined molecules.
| Molecular weight | 222.00 |
|---|---|
| Linear formula | FC6H4I |
| Assay | 99% |
| Boiling point | 188-189 °C(lit.) |
| Density | 1.903 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.59(lit.) |
| Contains / stabiliser | copper as stabilizer |
| Melting point | −41-−40 °C(lit.) |
| Application | 2-Fluoroiodobenzene was used in the synthesis of:• bridged biphenyl compounds, 1-fluoro-8-methylbiphenylene and 4-fluoro-5-methylfluorene1• 2-acetyl-7-iodo-1-benzothiophene2• chiral o-phosphanophenyl sulfoxides3 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-37/38-41-51/53 |
| Safety statements (S) | 26-39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoroiodobenzene used for?
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2-Fluoroiodobenzene is used as a building block in organic synthesis for the preparation of various complex molecules, including bridged biphenyl compounds, benzothiophene derivatives, and chiral sulfoxides.
What are the CAS number and formula for 2-Fluoroiodobenzene?
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The CAS number for 2-Fluoroiodobenzene is 348-52-7, and its chemical formula is FC6H4I.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoroiodobenzene with a purity of 99%. This product is intended for research and chemical synthesis and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety hazards associated with 2-Fluoroiodobenzene?
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2-Fluoroiodobenzene is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), and causes serious eye damage (H318). Appropriate personal protective equipment, including eyeshields, face shields, and gloves, must be used.
How is 2-Fluoroiodobenzene packed, shipped, and exported?
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2-Fluoroiodobenzene is carefully packed to ensure safe transit and is available for domestic and international export by Tech Serve Solutions, a specialist global supplier.
How can I request a quote or sample for 2-Fluoroiodobenzene?
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To request a quote or sample of 2-Fluoroiodobenzene, please contact the Tech Serve Solutions sales team via the website or by phone.
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