2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylic acid
2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylic acid (CAS: 1040681-74-0), with the molecular formula C7H3F4NO2 and a molecular weight of 209.10 g/mol, is a fluorinated heterocyclic building block. It serves as a valuable intermediate in organic synthesis, particularly within the pharmaceutical and agrochemical sectors, enabling the construction of complex fluorinated pyridine derivatives. Its precise structure facilitates targeted chemical transformations.
- IUPAC
- 2-Fluoro-4-(trifluoromethyl)nicotinic acid
- Synonyms
- 2-Fluoro-4-(trifluoromethyl)nicotinic acid
Pharmaceutical Intermediate
This compound is utilised as a key building block in the synthesis of novel pharmaceutical agents. Its fluorinated pyridine core is incorporated into drug candidates to modulate pharmacokinetic and pharmacodynamic properties.
Agrochemical Development
It finds application in the development of advanced agrochemicals. The trifluoromethyl and fluoro substituents can enhance the efficacy and stability of pesticides and herbicides.
Organic Synthesis Reagent
As a versatile building block, it is employed in diverse organic synthesis pathways. It allows for the introduction of a difluorinated pyridine moiety into various molecular frameworks.
| Molecular weight | 209.10 |
|---|---|
| Empirical formula | C7H3F4NO2 |
| Assay | 97% |
| Melting point | 95-100 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylic acid used for?
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2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylic acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What are the CAS number and formula for this compound?
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The CAS number is 1040681-74-0 and the empirical formula is C7H3F4NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical at a purity of 97%. It is suitable for research and general chemical synthesis. TSS does not represent this product as USP, BP, or EP grade.
How should 2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylic acid be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust, ensure good ventilation, and wear protective clothing. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring compliant packaging and international shipping procedures for research and industrial use.
How can I request a quote or sample?
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Please contact our sales team through our website or by phone to request a quote or sample of 2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylic acid.
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