N-(2-Chloro-3-hydroxypyridin-4-yl)pivalamide
N-(2-Chloro-3-hydroxypyridin-4-yl)pivalamide (CAS 1021339-26-3) is a halogenated pyridine building block with the molecular formula C10H13ClN2O2 and a molar mass of 228.68 g/mol. The trisubstituted pyridine core carries a reactive chloro group, a free hydroxyl and a pivalamide-protected amine, making it a versatile intermediate for chemical synthesis. Tech Serve Solutions supplies it as a research-grade fine chemical for medicinal-chemistry and discovery applications, with worldwide export.
- Synonyms
- N-(2-Chloro-3-hydroxypyridin-4-yl)pivalamideN-(2-chloro-3-hydroxy-4-pyridinyl)-2,2-dimethylpropanamide2,2-dimethyl-N-(2-chloro-3-hydroxypyridin-4-yl)propanamideCAS 1021339-26-3
Pharmaceutical and medicinal-chemistry intermediate
Serves as a heterocyclic building block in the synthesis of drug candidates and complex molecules. The substituted pyridine scaffold is a common motif in active pharmaceutical ingredients and pharmaceutical intermediates.
Functionalisable halogenated heterocycle
The 2-chloro substituent provides a handle for cross-coupling and nucleophilic substitution, while the 3-hydroxy and 4-pivalamide groups allow further selective derivatisation. This makes the compound useful for building libraries of pyridine analogues.
Protected aminopyridine reagent
The pivalamide group acts as a robust protecting group for the ring amine, enabling multi-step routes where the amine must be masked during downstream reactions and revealed later.
Research and discovery use
Applied in laboratory-scale chemical research, route scouting and structure-activity studies. Suited to discovery programmes that require well-defined, functional-rich pyridine intermediates.
| Molecular weight | 228.68 |
|---|---|
| Empirical formula | C10H13ClN2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(2-Chloro-3-hydroxypyridin-4-yl)pivalamide used for?
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It is used primarily as a building block and intermediate in chemical synthesis, especially medicinal and discovery chemistry. Its chloro, hydroxy and pivalamide-protected amino groups on a pyridine ring make it useful for cross-coupling, selective derivatisation and the preparation of more complex pyridine-based molecules.
What is the CAS number and molecular formula of N-(2-Chloro-3-hydroxypyridin-4-yl)pivalamide?
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Its CAS number is 1021339-26-3 and its molecular formula is C10H13ClN2O2, corresponding to a molecular weight of 228.68 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade fine chemical intended for synthesis and laboratory use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis stating the actual assay and batch specifications is provided on request.
How should N-(2-Chloro-3-hydroxypyridin-4-yl)pivalamide be handled and stored?
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No formal GHS classification is supplied for this product, so handle it as a research chemical of undetermined hazard using good laboratory practice: wear suitable gloves, eye protection and a lab coat, avoid dust, skin and eye contact, and work with adequate ventilation. Store in a tightly closed container in a cool, dry, well-ventilated place away from incompatible materials. Always review the Safety Data Sheet supplied with the consignment before use.
How is N-(2-Chloro-3-hydroxypyridin-4-yl)pivalamide packed, shipped and exported?
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It is packed in secure, clearly labelled laboratory containers sized to the order, from gram to bulk quantities, with appropriate inner protection. Tech Serve Solutions exports worldwide and supplies the relevant Certificate of Analysis and Safety Data Sheet with each shipment, arranging compliant freight and export documentation.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 1021339-26-3 and your required quantity and destination. We will respond with availability, lead time, documentation and a formal quotation, and can arrange a sample where appropriate.
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