2-Fluoro-4-(trifluoromethyl)benzoyl chloride
2-Fluoro-4-(trifluoromethyl)benzoyl chloride (CAS: 126917-10-0) is a fluorinated organic compound with the molecular formula C8H3ClF4O. This acid halide serves as a valuable intermediate and building block in organic synthesis, particularly for introducing the 2-fluoro-4-(trifluoromethyl)benzoyl moiety into target molecules. Its reactivity makes it useful in the development of pharmaceuticals and agrochemicals.
Pharmaceutical Intermediate
This compound acts as a key building block in the synthesis of complex pharmaceutical ingredients. Its fluorinated structure can impart desirable properties to drug candidates, such as increased metabolic stability and lipophilicity.
Agrochemical Synthesis
2-Fluoro-4-(trifluoromethyl)benzoyl chloride is employed in the creation of novel agrochemicals. The trifluoromethyl group is known to enhance the biological activity of pesticides and herbicides.
Organic Synthesis Reagent
As a reactive acyl chloride, it is used to form esters, amides, and other carbonyl derivatives. It is particularly useful for introducing fluorinated aromatic groups in research and development settings.
| Molecular weight | 226.56 |
|---|---|
| Linear formula | FC6H3(CF3)COCl |
| Assay | 98% |
| Boiling point | 188-189 °C(lit.) |
| Density | 1.5 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.466(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-(trifluoromethyl)benzoyl chloride used for?
+
2-Fluoro-4-(trifluoromethyl)benzoyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It facilitates the introduction of the 2-fluoro-4-(trifluoromethyl)benzoyl group into target molecules.
What is the CAS number and formula for 2-Fluoro-4-(trifluoromethyl)benzoyl chloride?
+
The CAS number is 126917-10-0, and its linear formula is C8H3ClF4O (FC6H3(CF3)COCl).
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Fluoro-4-(trifluoromethyl)benzoyl chloride with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How is this chemical handled and shipped?
+
This compound is classified as corrosive (GHS05, Danger, H314). Handling requires appropriate personal protective equipment, including gloves, goggles, face shields, and suitable respiratory protection. It is shipped in accordance with international regulations for hazardous materials (UN 3265, Class 8, PG II).
Does Tech Serve Solutions export 2-Fluoro-4-(trifluoromethyl)benzoyl chloride?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-4-(trifluoromethyl)benzoyl chloride.
How can I request a quote or sample?
+
To request a quote or sample of 2-Fluoro-4-(trifluoromethyl)benzoyl chloride, please contact our sales department through the website or by calling our office.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis