2-Fluoro-4-biphenylylboronic acid
2-Fluoro-4-biphenylylboronic acid (CAS: 178305-99-2), with the molecular formula C12H10BFO2 and a molecular weight of 216.02 g/mol, is a disubstituted aryl boronic acid derivative. It serves as a valuable building block in organic synthesis, particularly for cross-coupling reactions. This compound is integral in the development of complex organic molecules, finding utility in pharmaceutical research and materials science applications where precise molecular architecture is required.
Suzuki-Miyaura Coupling Reagent
2-Fluoro-4-biphenylylboronic acid is widely employed as a key component in Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of carbon-carbon bonds, enabling the synthesis of substituted biaryl compounds.
Organic Synthesis Intermediate
This boronic acid derivative is a versatile intermediate for constructing complex organic frameworks. Its specific structural features are leveraged in multi-step syntheses within academic and industrial research settings.
Pharmaceutical Research
It acts as a crucial building block in the discovery and development of new pharmaceutical agents. The fluoro-biphenyl moiety can be incorporated into potential drug candidates to modulate their pharmacological properties.
Materials Science
The compound can be utilised in the synthesis of novel organic materials with specific electronic or optical properties, contributing to advancements in fields such as organic electronics.
| Molecular weight | 216.02 |
|---|---|
| Linear formula | FC6H3(C6H5)B(OH)2 |
| Melting point | 243-248 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-biphenylylboronic acid primarily used for?
+
2-Fluoro-4-biphenylylboronic acid is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions and as a versatile intermediate in organic synthesis, particularly for constructing complex biaryl structures relevant to pharmaceutical research and materials science.
What are the CAS number and molecular formula for 2-Fluoro-4-biphenylylboronic acid?
+
The CAS number is 178305-99-2, and the molecular formula is C12H10BFO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are technical/research grade, and we do not represent it as USP, BP, EP, or any other pharmacopoeia standard.
What are the safety and handling considerations for 2-Fluoro-4-biphenylylboronic acid?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK 2 in Germany, indicating it is hazardous to water.
How is 2-Fluoro-4-biphenylylboronic acid packed, shipped, and exported?
+
Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and adherence to all regulations for the safe and compliant shipment of this chemical worldwide.
How can I request a sample or quote for 2-Fluoro-4-biphenylylboronic acid?
+
To request a sample or obtain a quotation, please contact our sales team through the provided channels on the Tech Serve Solutions website, referencing the product name and CAS number.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis