2-Fluoro-4-hydroxybenzonitrile
2-Fluoro-4-hydroxybenzonitrile (CAS: 82380-18-5), with the molecular formula FC6H3(OH)CN and a molecular weight of 137.11 g/mol, is a specialised organic compound. It serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its unique structure, featuring both a nitrile and a hydroxyl group alongside a fluorine atom on an aromatic ring, allows for diverse chemical transformations.
Pharmaceutical Intermediate Synthesis
This compound is frequently employed in the synthesis of active pharmaceutical ingredients (APIs). The presence of the fluorine atom can modulate pharmacokinetic properties, while the nitrile and hydroxyl groups offer versatile reaction sites for further elaboration into complex drug molecules.
Agrochemical Development
2-Fluoro-4-hydroxybenzonitrile can be used as a key intermediate in the development of novel pesticides and herbicides. Its structural features may contribute to the efficacy and targeted action of agrochemical products.
Materials Science Research
The molecule's reactivity makes it a potential candidate for incorporation into advanced materials. Its derivatives could find applications in areas such as organic electronics or functional polymers.
Research and Development
As a fluorinated building block, it is a useful reagent for chemists exploring new synthetic routes and developing novel chemical entities in various research settings.
| Molecular weight | 137.11 |
|---|---|
| Linear formula | FC6H3(OH)CN |
| Assay | 99% |
| Melting point | 123-125 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-hydroxybenzonitrile used for?
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2-Fluoro-4-hydroxybenzonitrile is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals, and in materials science research.
What is the CAS number and chemical formula for 2-Fluoro-4-hydroxybenzonitrile?
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The CAS number is 82380-18-5, and the chemical formula is FC6H3(OH)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-4-hydroxybenzonitrile with a purity of 99%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Fluoro-4-hydroxybenzonitrile be handled?
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Handling requires caution due to its hazards. Wear appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Avoid dust formation and dispersion into air. It is harmful if swallowed, causes serious eye damage, and is toxic to aquatic life with long-lasting effects.
Is 2-Fluoro-4-hydroxybenzonitrile a controlled substance?
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The provided data does not indicate that 2-Fluoro-4-hydroxybenzonitrile is a controlled substance.
How is this chemical shipped or exported?
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The product is shipped under UN 3077 classification (Environmentally Hazardous Substance, Solid, N.O.S.) with Packing Group III.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the designated channels on the Tech Serve Solutions website, providing the product name and CAS number.
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