2-Chloropyrazine
2-Chloropyrazine (CAS: 14508-49-7), with the molecular formula C4H3ClN2, is a halogenated heterocyclic compound. This chemical serves as a valuable building block in organic synthesis, particularly in the development of novel pharmaceutical intermediates and agrochemicals. Its reactivity allows for diverse synthetic transformations, making it a key component in various chemical research and development pathways. TSS supplies this compound with a high assay for research and synthesis purposes.

Pharmaceutical Intermediate Synthesis
2-Chloropyrazine is utilised as a fundamental building block in the synthesis of complex pharmaceutical active ingredients. Its pyrazine core and chlorine substituent enable diverse derivatisation strategies for drug discovery programmes.
Agrochemical Development
This halogenated heterocycle finds application in the development of new agrochemicals, including herbicides and fungicides. Its structural features can be incorporated to enhance the efficacy and specificity of crop protection agents.
Organic Synthesis Reagent
As a versatile reagent, 2-Chloropyrazine is employed in various organic transformations. It facilitates the introduction of the pyrazine moiety into larger molecules, aiding in the construction of complex organic frameworks for research purposes.
| Molecular weight | 114.53 |
|---|---|
| Empirical formula | C4H3ClN2 |
| Assay | 97% |
| Boiling point | 153-154 °C(lit.) |
| Density | 1.283 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.539(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 57 °C / 134.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloropyrazine primarily used for?
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2-Chloropyrazine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates and agrochemicals.
What is the CAS number and molecular formula for 2-Chloropyrazine?
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The CAS number for 2-Chloropyrazine is 14508-49-7, and its molecular formula is C4H3ClN2.
What grade and purity does Tech Serve Solutions supply for 2-Chloropyrazine?
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Tech Serve Solutions supplies 2-Chloropyrazine with a minimum assay of 97%. TSS does not represent this product as USP, BP, or EP grade.
How should 2-Chloropyrazine be handled?
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2-Chloropyrazine is a flammable liquid and vapour (H226) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle in a well-ventilated area, away from ignition sources, wearing appropriate personal protective equipment including eyeshields and gloves. Avoid breathing vapours.
How is 2-Chloropyrazine packed and exported?
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2-Chloropyrazine is carefully packed according to international shipping regulations for hazardous materials and exported globally by TSS.
How can I request a sample or quote for 2-Chloropyrazine?
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To request a sample or quote for 2-Chloropyrazine, please contact the Tech Serve Solutions sales team via the website or listed contact details.
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