2-Chloropropionyl chloride
2-Chloropropionyl chloride (CAS: 7623-09-8) is a reactive organic compound with the linear formula CH3CHClCOCl and a molecular weight of 126.97 g/mol. As an acid halide and carbonyl compound, it serves as a valuable building block in organic synthesis. Its primary applications lie in the chemical industry for the preparation of various derivatives and as an intermediate in complex chemical manufacturing processes.

Organic Synthesis Intermediate
2-Chloropropionyl chloride is utilised as a key intermediate in the synthesis of diverse organic molecules. Its acyl chloride functionality allows for facile reactions such as esterification and amidation, enabling the construction of more complex structures.
Chemical Manufacturing
This compound finds application in the broader chemical industry as a reagent for introducing the 2-chloropropionyl group into other molecules. It is employed in the manufacturing pathways of speciality chemicals and pharmaceutical precursors.
Building Block for Heterocycles
The reactivity of 2-Chloropropionyl chloride makes it suitable for cyclisation reactions, contributing to the synthesis of heterocyclic compounds. These structures are often core components in medicinal chemistry and materials science.
| Molecular weight | 126.97 |
|---|---|
| Linear formula | CH3CHClCOCl |
| Assay | ≥95.0% (GC) |
| Boiling point | 109-111 °C(lit.) |
| Density | 1.281 g/mL at 20 °C1.308 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.440(lit.)n20/D 1.440 |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 26 °C / 78.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-35-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloropropionyl chloride used for?
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2-Chloropropionyl chloride (CAS: 7623-09-8) is primarily used as an intermediate and building block in organic synthesis and general chemical manufacturing.
What is the CAS number and formula for 2-Chloropropionyl chloride?
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The CAS number is 7623-09-8 and the linear formula is CH3CHClCOCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloropropionyl chloride with a purity of ≥95.0% (GC). This product is supplied for research and industrial purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Chloropropionyl chloride be handled?
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2-Chloropropionyl chloride is a dangerous substance (GHS02, GHS05, Danger) causing severe skin burns and eye damage (H314) and is flammable (H226). Handle with appropriate personal protective equipment including gloves, goggles, face shields, and respiratory protection in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling information.
How is 2-Chloropropionyl chloride packed and shipped?
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2-Chloropropionyl chloride is packed in compliance with international regulations for hazardous materials and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for 2-Chloropropionyl chloride?
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To request a quote or a sample of 2-Chloropropionyl chloride, please contact our sales team via the website or by phone, providing your details and the quantity required.
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