2-Chloropropionitrile
2-Chloropropionitrile (CAS: 1617-17-0, Formula: C3H4ClN, MW: 89.52) is a versatile organic building block and reagent. This compound serves as a key intermediate in chemical synthesis, particularly for nitrogen-containing compounds and cyanides/nitriles. It is utilized in the preparation of complex molecules, including pharmaceuticals and specialized polymers, demonstrating its importance in advanced organic chemistry research and development.
Polymerization Initiator
2-Chloropropionitrile acts as an initiator in atom-transfer radical polymerization, specifically used in single-pot synthesis of polyacrylonitrile under microwave irradiation.
Ionic Liquid Synthesis
It is employed in the synthesis of nitrile-functionalized methimazole-based ionic liquids, contributing to the development of novel ionic compound structures.
Natural Product Synthesis
The compound is utilised in the synthesis of complex natural products, such as the alkaloid (+)- and (-)-anatoxin, showcasing its utility in stereoselective synthesis.
| Molecular weight | 89.52 |
|---|---|
| Linear formula | CH3CH(Cl)CN |
| Assay | 95% |
| Boiling point | 120-122 °C(lit.) |
| Density | 1.012 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.413(lit.) |
| Application | 2-Chloropropionitrile was used as initiator during the single-pot atom-transfer radical polymerization under microwave irradiation for the synthesis of polyacrylonitrile1. It was used in the synthesis of:• nitrile functionalized methimazole-based ionic liquids2• (+)- and (-)-anatoxin3 |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 3275 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-23/24/25-36/37/38 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloropropionitrile used for?
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2-Chloropropionitrile is used as an initiator in polymerization processes and as a key intermediate in the synthesis of various organic compounds, including ionic liquids and natural products like anatoxin.
What are the CAS number and formula for 2-Chloropropionitrile?
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The CAS number for 2-Chloropropionitrile is 1617-17-0 and its linear formula is CH3CH(Cl)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloropropionitrile with a minimum assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloropropionitrile be handled safely?
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2-Chloropropionitrile is a Danger hazard, flammable (H226) and toxic if swallowed, in contact with skin, or if inhaled (H301, H311, H331). It causes skin irritation, serious eye irritation, and respiratory irritation (H315, H319, H335). Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
Is 2-Chloropropionitrile shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloropropionitrile, adhering to all international shipping regulations.
How can I request a quote or sample for 2-Chloropropionitrile?
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To request a quote or a sample of 2-Chloropropionitrile, please contact our sales team through the website or by phone, providing your contact details and required quantity.
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