2-Chloropyridine N-oxide hydrochloride
2-Chloropyridine N-oxide hydrochloride (CAS: 20295-64-1) is a chemical compound with the molecular formula C5H4ClNO · HCl and a molecular weight of 166.01 g/mol. This pyridine derivative serves as a valuable building block in organic synthesis, particularly in the preparation of halogenated heterocyclic compounds. It is frequently employed in the synthesis of various functionalized pyridines and related heterocycles for research and development purposes in chemical and pharmaceutical industries.
Synthesis of Aminoheterocyclic Analogs
2-Chloropyridine N-oxide hydrochloride is utilised as a key intermediate in the preparation of aminoheterocyclic analogs. This application is crucial for the development of new pharmaceutical candidates and biologically active molecules.
Preparation of 2-Aminopyridine Derivatives
The compound is employed in synthetic routes leading to various 2-aminopyridine derivatives. These derivatives are important scaffolds in medicinal chemistry and materials science.
Enzyme Assays
It has found application in biochemical research, specifically in benzyl viologen enzyme assays of membrane fractions. This aids in understanding cellular processes and enzyme kinetics.
| Molecular weight | 166.01 |
|---|---|
| Empirical formula | C5H4ClNO · HCl |
| Assay | 97% |
| Application | 2-Chloropyridine N-oxide hydrochloride was used in the synthesis of aminoheterocyclic analogs1 and 2-aminopyridine derivatives2. It was also used in benzyl viologen enzyme assay of membrane fractions3. |
| Melting point | 140-142 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloropyridine N-oxide hydrochloride used for?
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2-Chloropyridine N-oxide hydrochloride is primarily used as a building block in organic synthesis, particularly for preparing aminoheterocyclic analogs and 2-aminopyridine derivatives. It is also used in biochemical research for enzyme assays.
What are the CAS number and formula for 2-Chloropyridine N-oxide hydrochloride?
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The CAS number for 2-Chloropyridine N-oxide hydrochloride is 20295-64-1, and its empirical formula is C5H4ClNO · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloropyridine N-oxide hydrochloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling 2-Chloropyridine N-oxide hydrochloride?
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2-Chloropyridine N-oxide hydrochloride is classified as a Warning substance, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, should be worn. Ensure adequate ventilation.
How is 2-Chloropyridine N-oxide hydrochloride shipped?
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2-Chloropyridine N-oxide hydrochloride is shipped and exported according to regulations, identified under UN 2811, Class 6.1, Packaging Group III.
How can I request a quote or sample?
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To request a quote or a sample of 2-Chloropyridine N-oxide hydrochloride, please contact our sales team through the provided channels on our website.
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