2-Chloropyridine-3-boronic acid
2-Chloropyridine-3-boronic acid (CAS: 381248-04-0) is an organoboron compound with the molecular formula C5H5BClNO2 and a molecular weight of 157.36 g/mol. It typically presents as a solid and is primarily utilised as a building block in organic synthesis, particularly in cross-coupling reactions. The compound may contain varying amounts of its anhydride.
- IUPAC
- (2-Chloro-3-pyridyl)boronic acid,(2-Chloropyridin-3-yl)boronic acid,Dihydroxy(2-chloro-3-pyridyl)borane
- Synonyms
- (2-Chloro-3-pyridyl)boronic acid(2-Chloropyridin-3-yl)boronic acidDihydroxy(2-chloro-3-pyridyl)borane
Organic Synthesis Intermediate
Serves as a key reagent in the synthesis of complex organic molecules. Its utility is prominent in Suzuki-Miyaura coupling reactions for the formation of carbon-carbon bonds.
Pharmaceutical Research
Incorporated into synthetic routes for the development of novel pharmaceutical compounds. The pyridine and boronic acid functionalities offer versatile points for molecular elaboration.
Materials Science
Can be employed in the creation of functional materials, leveraging its unique structural features in polymer or supramolecular chemistry.
| Molecular weight | 157.36 |
|---|---|
| Empirical formula | C5H5BClNO2 |
| Storage temperature | 2-8°C |
| Application | May contain varying amounts of anhydride |
| Melting point | 121-134 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloropyridine-3-boronic acid used for?
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2-Chloropyridine-3-boronic acid is primarily used as an intermediate in organic synthesis, particularly for cross-coupling reactions like the Suzuki-Miyaura coupling, and in pharmaceutical research for developing new drug candidates.
What is the CAS number and molecular formula for 2-Chloropyridine-3-boronic acid?
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The CAS number is 381248-04-0 and the molecular formula is C5H5BClNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloropyridine-3-boronic acid as a research-grade chemical. The assay is not specified beyond 'May contain varying amounts of anhydride'. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling 2-Chloropyridine-3-boronic acid?
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This compound is classified with GHS07 symbol and 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid breathing dust.
How is 2-Chloropyridine-3-boronic acid packed and shipped?
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2-Chloropyridine-3-boronic acid is typically stored at 2-8°C. It is packed and exported according to international shipping regulations for chemical compounds.
How can I request a quote or sample for 2-Chloropyridine-3-boronic acid?
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To request a quote or sample, please contact our sales team through the website or by phone, specifying the product name and CAS number (381248-04-0).
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