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2-Furoyl chloride

CAS 527-69-5C5H3ClO2Chemical Synthesis

2-Furoyl chloride (CAS 527-69-5, C5H3ClO2) is a reactive acyl chloride derived from furoic acid. With a molecular weight of 130.53 g/mol, this heterocyclic compound is primarily utilised as a versatile building block in organic synthesis. It serves as a key intermediate for introducing the 2-furoyl moiety into various molecular structures, finding applications in the characterisation of specific alcohol mixtures and the preparation of specialised anhydrides.

IUPAC
Furan-2-carbonyl chloride
Synonyms
Furan-2-carbonyl chloride
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2-Furoyl chloride (C5H3ClO2) — chemical structure, CAS 527-69-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C7Chemical SynthesisFuransHeterocyclic Building Blocks
01 /Applications

Characterisation of Polyethoxylated Alcohols

2-Furoyl chloride is employed in analytical chemistry for the characterisation of complex mixtures containing polyethoxylated alcohols and their sulphate derivatives, aiding in precise compositional analysis.

Preparation of Dithiocarbonic Anhydrides

This reagent is utilised in synthetic organic chemistry for the preparation of S-2-furoyl-O-alkyldithiocarbonic anhydrides, contributing to the synthesis of novel chemical entities.

Heterocyclic Synthesis

As a furan derivative and an acyl chloride, it serves as a valuable building block in heterocyclic chemistry for the construction of more complex molecular frameworks.

02 /Properties
Molecular weight130.53
Empirical formulaC5H3ClO2
Assay95%
Boiling point173-174 °C(lit.)
Density1.324 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.531(lit.)
Application2-Furoyl chloride is used in the chararcterisation of mixtures of polyethoxylated alcohols and their sulphates1. It was also used in the preparation of S-2-furoyl-O-alkyldithiocarbonic anhydrides2.
Melting point−2 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point85 °C / 185 °F
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
527-69-5
MDL number
MFCD00003228
PubChem substance
24848981
Beilstein registry
110144
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Furoyl chloride used for?

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2-Furoyl chloride is used in the characterisation of mixtures of polyethoxylated alcohols and their sulphates, and in the preparation of S-2-furoyl-O-alkyldithiocarbonic anhydrides. It also functions as a heterocyclic building block in chemical synthesis.

What are the CAS number and formula for 2-Furoyl chloride?

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The CAS number for 2-Furoyl chloride is 527-69-5, and its molecular formula is C5H3ClO2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Furoyl chloride with an assay of 95%. This product is intended for research and general chemical use; TSS does not represent it as USP, BP, EP, or pharmaceutical grade.

How should 2-Furoyl chloride be handled safely?

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2-Furoyl chloride is a corrosive substance (H314). Handle with extreme care, wearing appropriate personal protective equipment including a faceshield, goggles, gloves, and a suitable respirator (e.g., ABEK type). Ensure adequate ventilation and refer to the Safety Data Sheet for detailed handling procedures.

Is 2-Furoyl chloride a controlled substance?

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The provided data does not indicate that 2-Furoyl chloride (CAS 527-69-5) is a controlled substance.

How is 2-Furoyl chloride packed and exported?

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2-Furoyl chloride is packed and shipped according to stringent international regulations for hazardous materials (UN 3265, Class 8, PG II). TSS exports globally, adhering to all relevant transport and customs requirements.

How can I request a quote or sample?

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To request a quote or a sample of 2-Furoyl chloride, please contact the Tech Serve Solutions sales department via our website or direct contact details, specifying your requirements.

Need 2-Furoyl chloride in a specific grade or volume?