2-Chloropyridine-4-carbonyl chloride
2-Chloropyridine-4-carbonyl chloride (CAS: 65287-34-5; Formula: C6H3Cl2NO; Molar Mass: 176.00 g/mol) is a halogenated heterocyclic compound. This reactive acyl chloride serves as a crucial intermediate and building block in organic synthesis, particularly for the introduction of the 2-chloropyridine-4-carbonyl moiety into more complex molecules. Its applications are found in the development of novel chemical entities within research and development settings.
- IUPAC
- 2-Chloroisonicotinoyl chloride
Organic Synthesis Intermediate
2-Chloropyridine-4-carbonyl chloride is employed as a versatile building block in the synthesis of various organic compounds. It facilitates the incorporation of the 2-chloropyridine-4-carbonyl group, which is valuable in medicinal chemistry and materials science research.
Pharmaceutical Research
This compound is utilised in the exploration of new pharmaceutical agents. Its structure allows for derivatisation into potential drug candidates targeting a range of therapeutic areas.
Heterocyclic Chemistry
As a functionalised pyridine derivative, it is a key reagent for constructing complex heterocyclic systems. It is particularly useful in reactions requiring an electrophilic pyridine derivative.
| Molecular weight | 176.00 |
|---|---|
| Empirical formula | C6H3Cl2NO |
| Assay | 97% |
| Boiling point | 144-148 °C/10 mmHg |
| Density | 1.418 g/mL at 25 °C |
| Refractive index | n20/D 1.566 |
Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 25-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloropyridine-4-carbonyl chloride used for?
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2-Chloropyridine-4-carbonyl chloride (CAS: 65287-34-5) is primarily used as a building block and intermediate in organic synthesis, particularly for introducing the 2-chloropyridine-4-carbonyl moiety into target molecules for pharmaceutical and chemical research.
What is the CAS number and formula for 2-Chloropyridine-4-carbonyl chloride?
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The CAS number is 65287-34-5, and the empirical formula is C6H3Cl2NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloropyridine-4-carbonyl chloride with a minimum assay of 97%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP.
How should 2-Chloropyridine-4-carbonyl chloride be handled safely?
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Handling requires extreme caution due to its corrosive and toxic nature. It is labelled with Danger signal word and carries hazard statements H301 (Toxic if swallowed) and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including faceshields, gloves, goggles, and suitable respirators (e.g., US: multi-purpose combination respirator cartridge, type ABEK (EN14387) respirator filter), must be worn. Ensure good ventilation.
Is 2-Chloropyridine-4-carbonyl chloride available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloropyridine-4-carbonyl chloride, adhering to all relevant shipping and regulatory requirements.
How can I request a quote or sample?
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To request a quote or a sample of 2-Chloropyridine-4-carbonyl chloride, please contact our sales team through the website or by phone, providing your details and the quantity required.
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