Thioflavin T

CAS 2390-54-7C17H19ClN2SCell Biology

Thioflavin T (CAS: 2390-54-7), with the molecular formula C17H19ClN2S and a molecular weight of 318.86 g/mol, is a benzothiazole dye. It exhibits increased fluorescence upon binding to amyloid structures. This property makes it valuable for applications in histology and for the characterisation of proteins, particularly in cell biology research. TSS supplies Thioflavin T for laboratory and research use.

IUPAC: Basic Yellow 1,Thioflavine T
Synonyms: Basic Yellow 1Thioflavine T

Email us

Thioflavin T (C17H19ClN2S) — chemical structure, CAS 2390-54-7; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyHematology and HistologyStains & DyesA to ZStains and DyesT-U-V

01 /Applications

Amyloid Detection

Thioflavin T is a fluorescent dye that specifically binds to amyloid fibrils. This binding event causes a significant increase in fluorescence, enabling the detection and visualization of amyloid aggregates in biological samples.

Protein Characterization

The dye's interaction with amyloidogenic proteins allows for their characterization. Its fluorescence properties can be used to study protein folding, aggregation kinetics, and conformational changes.

Histology Staining

In histology, Thioflavin T serves as a stain to highlight amyloid deposits within tissue sections. This aids in the pathological diagnosis of amyloidosis and other related conditions.

Cell Biology Research

Utilized in cell biology, Thioflavin T assists in the investigation of cellular processes involving protein aggregation and amyloid formation. Its fluorescence aids in understanding the cellular mechanisms underlying these phenomena.

02 /Properties

Molecular weight	318.86
Empirical formula	C17H19ClN2S
Solubility	methanol: soluble1 mg/mL
Application	Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid.1,2 Thioflavin T has been used in histology and for protein characterization.3

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2390-54-7

MDL number

MFCD00011944

PubChem substance

24900146

Beilstein registry

3922452

05 /Additional specifications

Colour Index Number	49005

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Thioflavin T used for?

Thioflavin T is primarily used as a fluorescent dye for the detection and characterization of amyloid structures in biological samples, including histology and protein studies.

What are the CAS number and chemical formula for Thioflavin T?

The CAS number for Thioflavin T is 2390-54-7, and its chemical formula is C17H19ClN2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Thioflavin T for research purposes. The specific grade and purity available are detailed in the product specifications; TSS does not represent this product as USP, BP, or EP grade.

What are the safety and handling considerations for Thioflavin T?

Thioflavin T is classified under WGK Germany 3. When handling, it is essential to use personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter.

How is Thioflavin T packed, shipped, and exported?

Tech Serve Solutions carefully packs and handles all chemicals, including Thioflavin T, in compliance with international shipping regulations for global export.