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1-(2-Hydroxyethyl)-2-pyrrolidone

CAS 3445-11-2C6H11NO2Chemical Synthesis

1-(2-Hydroxyethyl)-2-pyrrolidone (CAS 3445-11-2; C6H11NO2; molar mass 129.16 g/mol) is an N-substituted pyrrolidinone bearing a primary hydroxyl group on its ethyl side chain. Supplied by Tech Serve Solutions at 98% assay, it is a clear, higher-boiling liquid valued as a polar aprotic-type solvent and heterocyclic building block. Its reactive hydroxyl makes it a useful intermediate for further functionalisation in chemical synthesis, research and specialty formulation work.

Synonyms
1-(2-Hydroxyethyl)-2-pyrrolidone1-(2-Hydroxyethyl)-2-pyrrolidinoneN-(2-Hydroxyethyl)-2-pyrrolidoneN-(2-Hydroxyethyl)pyrrolidone1-(2-Hydroxyethyl)pyrrolidin-2-one2-(2-Oxopyrrolidin-1-yl)ethanolN-(2-Hydroxyethyl)-2-pyrrolidinoneHEP
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1-(2-Hydroxyethyl)-2-pyrrolidone (C6H11NO2) — chemical structure, CAS 3445-11-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C8Chemical SynthesisHeterocyclic Building BlocksPyrrolidines
01 /Applications

Heterocyclic building block

Used as a pyrrolidinone-based intermediate in chemical synthesis, where the lactam ring and pendant hydroxyl group provide a versatile handle for esterification, etherification and onward derivatisation.

Polar solvent and reaction medium

The pyrrolidone backbone confers strong polarity and a high boiling point, making it suitable as a solvent or co-solvent for reactions and formulations requiring good dissolving power.

Specialty intermediate for functionalised derivatives

The reactive primary alcohol allows preparation of acrylates, ethers and other hydroxy-functional derivatives used in coatings, polymers and fine-chemical chemistry.

Laboratory and research reagent

Employed in research and development settings as a defined-purity reagent for synthesis, screening and method-development work.

02 /Properties
Molecular weight129.16
Empirical formulaC6H11NO2
Assay98%
Boiling point140-142 °C/3 mmHg(lit.)
Density1.143 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.496(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point100 °C / 212 °F
Water hazard class (WGK, DE)2
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
3445-11-2
MDL number
MFCD00014103
PubChem substance
24859862
Beilstein registry
112181
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-(2-Hydroxyethyl)-2-pyrrolidone used for?

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It is used mainly as a heterocyclic building block and intermediate in chemical synthesis, and as a polar, high-boiling solvent. Its primary hydroxyl group is readily functionalised, supporting the preparation of esters, ethers and other hydroxy-functional derivatives for specialty and research applications.

What is the CAS number and molecular formula of 1-(2-Hydroxyethyl)-2-pyrrolidone?

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The CAS number is 3445-11-2 and the molecular formula is C6H11NO2, with a molecular weight of 129.16 g/mol. Related identifiers include EC number 222-359-4, MDL number MFCD00014103 and Beilstein registry number 112181.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 1-(2-Hydroxyethyl)-2-pyrrolidone at a typical assay of 98%, as a technical/research-grade material. We do not represent it as USP, BP or EP pharmacopoeia grade. A specification or certificate of analysis can be provided with each consignment on request.

What are the safety and handling requirements for 1-(2-Hydroxyethyl)-2-pyrrolidone?

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It carries GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves and eye protection, use suitable respiratory protection and adequate ventilation, and avoid generating mist or vapour. It is classified WGK 2 (water-hazard class). Always consult the Safety Data Sheet before use.

How is 1-(2-Hydroxyethyl)-2-pyrrolidone packed, shipped and exported?

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The product is supplied in securely sealed, appropriately labelled containers sized to laboratory and bulk requirements, with full documentation. As a specialist exporter, Tech Serve Solutions arranges compliant international shipping with the relevant SDS and transport paperwork. Packing details are confirmed at the time of order.

How do I request a sample or quote?

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Contact Tech Serve Solutions with your required quantity, purity and delivery destination, and our team will respond with availability, lead time and a formal quotation. Samples can be discussed for qualification purposes subject to availability.

Need 1-(2-Hydroxyethyl)-2-pyrrolidone in a specific grade or volume?