Z-Lys(Z)-OH
N,N′-Di-Cbz-L-lysine (CAS 405-39-0) is a protected amino acid derivative with the linear formula C6H5CH2O2CNH(CH2)4CH(NHCO2CH2C6H5)CO2H. This compound, with a molecular weight of 414.45, serves as a valuable building block in chemical synthesis, particularly in peptide chemistry and biochemical research. Its protected nature allows for controlled reactions in complex organic synthesis pathways.
- IUPAC
- N,N′-Di-Cbz-L-lysine,Nα,Nε-Di-Z-L-lysine
- Synonyms
- N,N′-Di-Cbz-L-lysineNα,Nε-Di-Z-L-lysine

Peptide Synthesis
N,N′-Di-Cbz-L-lysine is utilized in solid-phase and solution-phase peptide synthesis. The Cbz protecting groups on the alpha-amino and epsilon-amino functionalities allow for regioselective coupling reactions.
Chemical Biology Research
As a derivative of lysine, this compound can be incorporated into biomolecules or used in studies exploring protein structure and function. Its protected form is essential for specific experimental designs.
Organic Synthesis Intermediate
The compound acts as a versatile intermediate in the synthesis of complex organic molecules. The presence of two protecting groups facilitates its use in multi-step synthetic routes requiring controlled reactivity.
| Molecular weight | 414.45 |
|---|---|
| Linear formula | C6H5CH2O2CNH(CH2)4CH(NHCO2CH2C6H5)CO2H |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N′-Di-Cbz-L-lysine used for?
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N,N′-Di-Cbz-L-lysine is primarily used as a building block in peptide synthesis, chemical biology research, and as an intermediate in organic synthesis.
What is the CAS number and linear formula for N,N′-Di-Cbz-L-lysine?
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The CAS number for N,N′-Di-Cbz-L-lysine is 405-39-0, and its linear formula is C6H5CH2O2CNH(CH2)4CH(NHCO2CH2C6H5)CO2H.
What grade and purity does Tech Serve Solutions supply for Z-Lys(Z)-OH?
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Tech Serve Solutions supplies Z-Lys(Z)-OH with an assay of ≥98.0% (TLC). This product is supplied for research and laboratory use and is not represented as USP, BP, or EP grade.
What are the safety considerations when handling N,N′-Di-Cbz-L-lysine?
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Handle N,N′-Di-Cbz-L-lysine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for comprehensive handling information.
How is N,N′-Di-Cbz-L-lysine typically packed and shipped?
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N,N′-Di-Cbz-L-lysine is carefully packed in suitable containers to ensure stability during transit and exported according to international shipping regulations for chemical compounds.
How can I request a sample or a quote for N,N′-Di-Cbz-L-lysine?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing your specific requirements.
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