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Z-Leu-Leu-Leu-al

CAS 133407-82-6C26H41N3O5Chemical Synthesis

Z-Leu-Leu-Leu-al (CAS: 133407-82-6), with the molecular formula C26H41N3O5 and a molecular weight of 475.62 g/mol, is a chemical compound offered by Tech Serve Solutions. It functions as a potent inhibitor in biochemical research, specifically targeting proteasome and calpain activity. Supplied as a powder, this compound is valuable for studies in cell biology, signalling pathways, and enzyme inhibition.

IUPAC
MG132
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Z-Leu-Leu-Leu-al (C26H41N3O5) — chemical structure, CAS 133407-82-6; Chemistry, fine chemical supplied by Tech Serve Solutions
AldehydesApplication IndexBioactive Small MoleculesBiochemicals and ReagentsBuilding BlocksC13-C60Carbonyl CompoundsCell BiologyCell Signaling EnzymesChemical Synthesis
01 /Applications

Proteasome Inhibition

Z-Leu-Leu-Leu-al serves as a chemical probe for inhibiting proteasome activity. This application is crucial for researchers investigating cellular protein degradation pathways and their role in various biological processes.

Calpain Inhibition

This compound is utilized as an inhibitor of calpain, a family of calcium-dependent cysteine proteases. Its use aids in the study of calpain's involvement in cell signalling, apoptosis, and other physiological events.

Biochemical Research

As a bioactive small molecule, Z-Leu-Leu-Leu-al is employed in diverse biochemical research settings. It aids in understanding enzyme mechanisms and exploring cellular functions related to protein processing.

Cell Signaling Studies

The compound's ability to modulate enzyme activity makes it a useful tool for researchers exploring cell signalling cascades and their downstream effects in biological systems.

02 /Properties
Molecular weight475.62
Empirical formulaC26H41N3O5
Assay≥90% (HPLC)
Formpowder
SolubilityDMSO: soluble
Storage temperature−20°C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
133407-82-6
MDL number
MFCD00674886
PubChem substance
24892475
05 /Additional specifications
Gene Informationhuman ... CTSB(1508), NFKB1(4790), PSMA1(5682)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Z-Leu-Leu-Leu-al primarily used for?

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Z-Leu-Leu-Leu-al is primarily used as an inhibitor of proteasome and calpain activity in biochemical and cell biology research.

What are the CAS number and molecular formula for Z-Leu-Leu-Leu-al?

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The CAS number for Z-Leu-Leu-Leu-al is 133407-82-6, and its molecular formula is C26H41N3O5.

What grade and purity does Tech Serve Solutions supply for Z-Leu-Leu-Leu-al?

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Tech Serve Solutions supplies Z-Leu-Leu-Leu-al with a purity of ≥90% (HPLC). We do not represent this product as USP, BP, EP, or pharmaceutical grade.

How should Z-Leu-Leu-Leu-al be handled safely?

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Safe handling of Z-Leu-Leu-Leu-al requires the use of eyeshields and gloves. In environments with potential airborne dust, a type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified with WGK Germany 3.

How is Z-Leu-Leu-Leu-al typically shipped and exported?

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Z-Leu-Leu-Leu-al is shipped and exported according to relevant chemical transport regulations. For international shipments, please contact our export department for specific documentation and compliance.

How can I request a sample or quote for Z-Leu-Leu-Leu-al?

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To request a sample or quote for Z-Leu-Leu-Leu-al, please use the contact form on our website or reach out to our sales team directly.

What is the recommended storage temperature for Z-Leu-Leu-Leu-al?

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Z-Leu-Leu-Leu-al should be stored at −20°C.

Need Z-Leu-Leu-Leu-al in a specific grade or volume?