Z-Leu-Leu-Norvalinal
Z-Leu-Leu-Norvalinal (CAS: 133407-86-0), a peptide aldehyde with the empirical formula C25H39N3O5, is supplied by Tech Serve Solutions. This compound is a valuable reagent in biochemical research, particularly for studying proteasome and calpain activity. It serves as a key building block in chemical synthesis and finds application in cell biology research, especially concerning cell signaling and endoplasmic reticulum stress pathways. Its precise molecular structure and inhibitory properties make it an important tool for understanding enzymatic processes.
- IUPAC
- MG115,Z-LLnV

Proteasome and Calpain Inhibition
Z-Leu-Leu-Norvalinal is utilised as an inhibitor for proteasome and calpain enzymes. These enzymes are critical in cellular protein degradation pathways, and their inhibition is studied in various biological contexts.
Cell Signaling Research
This compound serves as a research tool in cell signaling studies, including investigations into endoplasmic reticulum stress. It aids in dissecting complex cellular communication pathways.
Biochemical Studies
As a bioactive small molecule, Z-Leu-Leu-Norvalinal is employed in diverse biochemical experiments. Its specific interactions can elucidate enzyme mechanisms and cellular functions.
Chemical Synthesis Building Block
The molecule's structure makes it a useful building block in organic and medicinal chemistry synthesis. It can be incorporated into more complex molecular designs.
| Empirical formula | C25H39N3O5 |
|---|---|
| Assay | ≥90% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: soluble |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PSMA1(5682), PSMC1(5700)mouse ... PSMA1(26440), PSMC1(19179)rat ... PSMA1(29668), PSMC1(117263) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Leu-Leu-Norvalinal used for?
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Z-Leu-Leu-Norvalinal is primarily used as a research chemical, notably as an inhibitor of proteasome and calpain enzymes, and in studies of cell signaling and endoplasmic reticulum stress.
What are the CAS number and formula for Z-Leu-Leu-Norvalinal?
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The CAS number for Z-Leu-Leu-Norvalinal is 133407-86-0, and its empirical formula is C25H39N3O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-Leu-Leu-Norvalinal with a purity of ≥90% (HPLC). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should Z-Leu-Leu-Norvalinal be handled?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling Z-Leu-Leu-Norvalinal. The product is classified with WGK Germany 3.
How is Z-Leu-Leu-Norvalinal shipped and exported?
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Z-Leu-Leu-Norvalinal is stored at -20°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of handling international shipments.
How can I request a quote or sample?
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To request a quote or sample of Z-Leu-Leu-Norvalinal, please contact Tech Serve Solutions directly through our sales channels.
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