Z-Lys-ONp hydrochloride
Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride (CAS 2179-15-9) is a protected amino acid derivative with the molecular formula C20H23N3O6 · HCl and a molecular weight of 437.87 g/mol. This compound serves as a valuable reagent in biochemical research, particularly as a substrate for enzyme activity assays. Its controlled chemical structure makes it useful in studies involving peptide synthesis and chemical biology.
- IUPAC
- Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride
- Synonyms
- Nα-Benzyloxycarbonyl-L-lysine 4-nitrophenyl ester hydrochloride
Enzyme Substrate
This compound is frequently employed as a chromogenic substrate for enzyme activity determination. Upon enzymatic cleavage, the 4-nitrophenyl group is released, producing a measurable yellow colour that can be quantified spectrophotometrically.
Peptide Synthesis Reagent
As a protected lysine derivative, it can be incorporated into peptide sequences during solid-phase or solution-phase synthesis. The benzyloxycarbonyl (Z) group provides protection for the alpha-amino function, facilitating controlled peptide chain elongation.
Chemical Biology Research
Its specific reactivity makes it useful in probing enzyme mechanisms and developing biochemical assays. It aids in understanding enzyme kinetics and the role of specific amino acid residues in biological processes.
| Molecular weight | 437.87 |
|---|---|
| Empirical formula | C20H23N3O6 · HCl |
| Assay | ≥98.0% (AT) |
| Optical activity | [α]20/D −24±1°, c = 1% in DMF |
| Storage temperature | −20°C |
| Melting point | 146-152 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride used for?
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Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride is primarily used as a substrate for enzyme assays, particularly for enzymes that cleave ester bonds, and in peptide synthesis research.
What are the CAS number and chemical formula for Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride?
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The CAS number is 2179-15-9 and the chemical formula is C20H23N3O6 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride with an assay of ≥98.0% (AT). This product is intended for laboratory and research use; it is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride be stored and handled?
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This compound should be stored at -20°C. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Avoid contact with skin and eyes, and do not inhale dust.
Is Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride a controlled substance?
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Based on the provided data, there is no indication that Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride is a controlled substance. However, users should always comply with local regulations.
How can I request a sample or quote for Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride?
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To request a sample or a quotation, please contact our sales department via the website or provide your details through the online enquiry form. We are a global supplier and exporter.
What are the physical properties of Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride?
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It has a melting point of 146-152°C and exhibits optical activity of [α]20/D −24±1°, c = 1% in DMF.
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