Z-Glu-OMe
Z-Glu-OMe (CAS: 5672-83-3) is a derivative of glutamic acid with the linear formula HOOCCH₂CH₂CH(NHCOOCH₂C₆H₅)COOCH₃ and a molecular weight of 295.29 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its defined stereochemistry and functional groups make it suitable for complex molecular constructions. Tech Serve Solutions supplies this high-purity reagent for advanced laboratory applications.
- IUPAC
- N-Carbobenzyloxy-L-glutamic acid 1-methyl ester,Z-L-Glutamic acid 1-methyl ester
- Synonyms
- N-Carbobenzyloxy-L-glutamic acid 1-methyl esterZ-L-Glutamic acid 1-methyl ester
Peptide Synthesis
Z-Glu-OMe is utilised as a protected amino acid derivative in the synthesis of peptides. The N-benzyloxycarbonyl (Z) group and the methyl ester protect the amine and carboxylic acid functionalities, respectively, allowing for controlled coupling reactions.
Chemical Biology Research
In chemical biology, this compound can be employed in the development of modified peptides or as a starting material for creating biologically active molecules. Its structure allows for further functionalization and incorporation into complex biological probes.
Organic Synthesis Intermediate
As a versatile intermediate, Z-Glu-OMe finds application in general organic synthesis where a chiral glutamic acid derivative is required. It facilitates the construction of intricate molecular architectures.
| Molecular weight | 295.29 |
|---|---|
| Linear formula | HOOCCH2CH2CH(NHCOOCH2C6H5)COOCH3 |
| Assay | ≥99.0% (sum of enantiomers, TLC) |
| Optical activity | [α]20/D −24.0±1°, c = 1% in ethanol |
| Melting point | 64-69 °C68-70 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Glu-OMe used for?
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Z-Glu-OMe is used in peptide synthesis, chemical biology research, and as a versatile intermediate in organic synthesis, particularly for constructing complex molecules requiring a protected glutamic acid derivative.
What is the CAS number and formula for Z-Glu-OMe?
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The CAS number for Z-Glu-OMe is 5672-83-3. Its linear formula is HOOCCH₂CH₂CH(NHCOOCH₂C₆H₅)COOCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-Glu-OMe with an assay of ≥99.0% (sum of enantiomers, TLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations for handling Z-Glu-OMe?
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When handling Z-Glu-OMe, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is Z-Glu-OMe packed, shipped, and exported?
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Tech Serve Solutions ensures secure packaging for Z-Glu-OMe, suitable for domestic and international shipment. We are experienced exporters of fine chemicals, pharmaceutical intermediates, and laboratory reagents globally.
How can I request a sample or quote for Z-Glu-OMe?
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To request a sample or a quotation for Z-Glu-OMe, please contact our sales department through the website or by phone, providing your contact details and the required quantity.
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