Z-Gln-OH

CAS 2650-64-8NH2COCH2CH2CH(NHCOOCH2C6H5)COOHChemical Synthesis

Z-Gln-OH (CAS: 2650-64-8) is a protected amino acid derivative with a molecular weight of 280.28 g/mol. It is N-carbobenzyloxy-L-glutamine, commonly used in peptide synthesis and chemical biology research. This compound serves as a crucial building block for creating complex peptides and modified amino acids, offering researchers a reliable reagent for advancing scientific discovery in related fields.

IUPAC: N-Cbz-L-glutamine,Carbobenzyloxy-L-glutamine,Z-L-Glutamine
Synonyms: N-Cbz-L-glutamineCarbobenzyloxy-L-glutamineZ-L-Glutamine

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Z-Gln-OH (NH2COCH2CH2CH(NHCOOCH2C6H5)COOH) — chemical structure, CAS 2650-64-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisGlutaminePeptide Chemistry

01 /Applications

Peptide Synthesis

Z-Gln-OH is a protected form of L-glutamine, widely employed as a building block in solid-phase and solution-phase peptide synthesis. Its carbobenzyloxy (Z) protecting group facilitates controlled coupling reactions.

Chemical Biology

As an amino acid derivative, it finds application in chemical biology for the synthesis of modified peptides and peptidomimetics. These molecules are used to probe biological pathways and develop new therapeutic agents.

Organic Synthesis

The compound serves as a versatile intermediate in organic synthesis, allowing for the introduction of glutamine residues into various molecular structures. Its defined stereochemistry is critical for applications requiring specific biological activity.

02 /Properties

Molecular weight	280.28
Linear formula	NH2COCH2CH2CH(NHCOOCH2C6H5)COOH
Assay	≥99.0% (T)
Optical activity	[α]20/D −6.5±0.5°, c = 2% in ethanol
Melting point	134-138 °C(lit.)134-138 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2650-64-8

MDL number

MFCD00008043

PubChem substance

24849998

Beilstein registry

2061271

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Z-Gln-OH used for?

Z-Gln-OH is primarily used in peptide synthesis and chemical biology research as a protected form of L-glutamine for building peptide chains and creating modified amino acid derivatives.

What is the CAS number and formula for Z-Gln-OH?

The CAS number for Z-Gln-OH is 2650-64-8. Its linear formula is NH₂COCH₂CH₂CH(NHCOOCH₂C₆H₅)COOH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Z-Gln-OH with an assay of ≥99.0% (T). This product is not graded as USP, BP, EP or pharmaceutical grade unless explicitly stated in the product specifications.

How should Z-Gln-OH be handled safely?

Appropriate personal protective equipment, including eyeshields and gloves, should be worn when handling Z-Gln-OH. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3.

Is Z-Gln-OH a controlled substance?

Based on the provided data, Z-Gln-OH is not listed as a controlled substance.

How is Z-Gln-OH packed and shipped?

Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transport and handling according to international regulations.